globoside


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globoside

 [glob´o-sīd]
a sphingoglycolipid containing acetylated amino sugars and simple hexoses, occurring in human serum, spleen, liver, and erythrocytes, and accumulating in tissues in Sandhoff's disease.

glo·bo·side

(glō'bō-sīd),
A glycosphingolipid; specifically, a ceramide tetrasaccharide (tetraglycosylceramide), isolated from kidney and erythrocytes; accumulates in people with Sandhoff disease.

globoside

/glob·o·side/ (glob´o-sīd) a glycosphingolipid containing acetylated amino sugars and simple hexoses that accumulates in tissues in Sandhoff's disease but not in Tay-Sachs disease.

glo·bo·side

(glō'bō-sīd)
A glycosphingolipid isolated from kidney and erythrocytes; accumulates in patients with Sandhoff disease.
References in periodicals archive ?
The major neutral GSLs of tonsil lymphocytes are glucosyl ceramide, lactosyl ceramide, trihexasoyl ceramide and globoside.
The most abundant neutral GSLs are glucosyl and galactosyl ceramides, and globoside, the most abundant GSL of mature erythrocytes, was not detected.
We used rabbit antibodies to lactosyl ceramide and globoside to study their distribution in human tissues by immunofluorescence.
The total cell content of globoside was decreased by 30% but its cell surface expression was decreased 3-4 fold.
To determine the generality of our observations that globoside colocalizes intracellularly with intermediate filaments, and that its localization is modulated by IFN-gamma, we analyzed a variety of cell types.
1979) Reaction of antibodies that cause paroxysmal cold hemoglobinuria with globoside and Forssman glyco-sphingolipids.
1981) Immunochemical relationship between Forssman and globoside glycolipids.