globoid cell


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Related to globoid cell: gargoylism

glo·boid cell

a large cell of mesodermal origin that is found clustered in the intracranial tissues in globoid cell leukodystrophy.
References in periodicals archive ?
Krabbe's or globoid cell leukodystrophy also has predominant periventricular white matter involvement, but also has hypointense thalami due to calcifications (12) and early cerebellar involvement seen as alternating halos.
This year's "Best in Show" winner, Devon, as a West Highland terrier, is predisposed to a laundry list of genetic illnesses - including craniomandibular osteopathy (a disease also known as "Westie jaw"), skin disorders (like atopic dermatitis), neurological diseases (such as globoid cell leukodystrophy) and abdominal hernias, among other ailments.
- Globoid Cell Leukodystrophy (Krabbe Disease) Global Clinical Trials Review, H1, 2014
It includes Krabbe disease (KD) or globoid cell leukodystrophy (GLD), Canavan disease, Pelizaeus-Merzbacher disease and Alexander disease.