globin


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globin

 [glo´bin]
1. the protein constituent of hemoglobin.
2. any of a group of proteins similar to the typical globin.

glo·bin

(glō'bin),
The protein of hemoglobin; α-globin and β-globin represent the two types of chains found in adult hemoglobin.
Synonym(s): hematohiston

globin

(glō′bĭn)
n.
Any of a group of heme-containing proteins, including myoglobin and hemoglobin, that can bind oxygen and other gases.

glo·bin

(glō'bin)
The protein of hemoglobin; α-globin and β-globin represent the two types of chains found in adult hemoglobin.
Synonym(s): hematohiston.

globin

A term for the collection of four polypeptides in the haemoglobin molecule.

Globin

One of the component protein molecules found in hemoglobin. Normal adult hemoglobin has a pair each of alpha-globin and beta-globin molecules.

glo·bin

(glō'bin)
The protein of hemoglobin; α-globin and β-globin represent the two types of chains found in adult hemoglobin.
Synonym(s): hematohiston.
References in periodicals archive ?
Increased expression of I3 globin gene was seen in BT children who had XMNI polymorphism at position-158.
HbVar: A relational database of human hemoglobin variants and thalassemia mutations at the globin gene server.
All those with RNA replaced with beta globin UTRs reached a peak in fluorescent level at about 15 hr before subsequent decreasing, once the mRNA had all been translated and expressed in protein (Figure 2).
Globin Chain Separation: The globin was precipitated in cold acidified acetone.
Thalassemias are caused by mutations that reduce globin gene expression in red blood cell precursors.
Conversely, the counterpart anti-Lepore [beta][delta] fusion globin is not usually associated with hematological abnormalities.
This reaction leads to extensive cross-linking between the globin chains and oxidation of cysteine residues in [beta] globin protein, which further leads to heme degradation [37].
With the aim of determining the therapeutic potency of the novel inducing compounds and studying the underlying regulatory mechanism of the embryonic and fetal human globin genes expression, various in vitro and in vivo screening platforms have been widely utilized.
The pathophysiology of HbH disease results from imbalanced globin chain production [8], whereby the reduced [alpha]-globin chain synthesis results in precipitation of excess [beta]- or [gamma]-globin chains in RBC membrane [9] and eventual hemolysis [25].
This is because the disease involves unknown deletions and mutations, mutations in gene regulation sites, and mutations in genes generating trans-elements for globin gene expression (nonglobin gene related thalassemia).
Thalassemia encompasses a spectrum of hereditary anemias characterized by reduced or absent production of one or more globin chains [1].
Supply of globulin for the immunity (Amino Globin) of different contractions, also of human albumin 20 % concentration, metro-nidazol 500 mg in 100 cm3 vial for injection.