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A deliberately ingested her parent's glipizide and needs psychiatric admission
Schneider, Rapid extraction, identification and quantification of oral hypoglycaemic drugs (glipizide, glibenclamide, gliclazide, gliquidone and metformin) in serum and hair using LC- MS/MS, Forensic Sci.
Treatment was limited to supportive care and oral glipizide. Glipizide is a sulfonylurea drug that increases endogenous insulin secretion by interacting with sulfonylurea receptors or by inhibiting potassium channels on pancreatic beta cells.
[15] Amlodipine, Glipizide, Metformin, Prednisone, Propranolol, & Tacrolimus.
Mylan said the Glipizide Extended-release Tablets, 5 mg and 10 mg is generic version of Pfizer's GLUCOTROL XL.
And glibenclamide, gliquidone, glipizide and glimepiride are the common drugs in the class of sulfonylurea.
The other drugs are glimeperide gliclazide and glipizide which may be used in those who get frequent hypoglycaemic episodes with glibenclamide which is quite rare.
The most commonly prescribed two-drug combination was of metformin and glimepiride (9.3%) followed by metformin + voglibose (3.8%), metformin + pioglitazone (3.5%), metformin + glipizide (2.6%), metformin + insulin (1.6%), and metformin + glibenclamide (0.8%).
MEDICATION POTENTIAL INTERACTION Prescription diuretic (Lasix) Dehydration, electrolyte imbalance Lithium Increases side effects of lithium Blood-thinning medications Increased risk of bleeding (Coumadin, Plavix) Diabetes medications May reduce blood sugar levels (insulin, metformin, glipizide) too severely Antacids (i.e., Tums, Milk of Increases stomach acid and Magnesia) heartburn Ciproflaxin (Cipro, an Chinese dandelion lowers antibiotic) absorption Source:
The second generation sulfonylureas are more potent and include glimepiride, glipizide and glyburide.
The second-generation agents, glimepiride (Amaryl[R]), glipizide (Glucotrol[R] and Glucotrol XL[R]), and glyburide (Diabeta[R], Micronase[R], and Glynase[R]), have shorter half-lives and shorter onset of action than the first generation sulfonylureas such as chlorpropamide, (Diabinese[R]), tolazamide (Tolinase[R]), and tolbutamide (Orinase[R]).