glioblastoma

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Related to glioblastomas: meningiomas, gliomas

glioblastoma

 [gli″o-blas-to´mah]
any malignant astrocytoma.
glioblastoma multifor´me astrocytoma grade III or IV; a rapidly growing tumor, usually of the cerebral hemispheres, composed of spongioblasts, astroblasts, and astrocytes.

glioblastoma

/glio·blas·to·ma/ (gli″o-blas-to´mah) any malignant astrocytoma.
glioblastoma multifor´me  the most malignant type of astrocytoma, composed of spongioblasts, astroblasts, and astrocytes; it usually occurs in the brain but may occur in the brain stem or spinal cord.

glioblastoma

(glē′ō-blă-stō′mə, glī′-)
n. pl. glioblasto·mas or glioblasto·mata (-mə-tə)
A malignant tumor of the central nervous system, usually occurring in the cerebrum of adults.

glioblastoma

glioblastoma

Astrocytoma, grade III-IV, glioblastoma multiforme, malignant astrocytoma Neurosurgery A highly aggressive 1º brain tumor–BT arising in glia, comprising 30% of the 5000 new BTs/yr, US At risk occupations Anatomists, pathologists, dentists, ophthalmologists Treatment Poor response to surgery, chemotherapy, RT. See Gliadel® wafer.

glioblastoma

an undifferentiated malignant astrocytoma.

glioblastoma multiforme
a rapidly growing tumor, usually of the cerebral hemispheres, often supratentorial.
References in periodicals archive ?
City of Hope researchers recently reported in the New England Journal of Medicine on the successful treatment of a patient with recurrent multifocal glioblastoma using CAR-T therapy to effectively attack cells with the IL13Ra2 antigen.
The researchers showed that Zika virus can kill the kind of glioblastoma cells that tend to be resistant to current treatments and lead to death.
But now researchers believe the harmful virus could have the potential to act as a surprising treatment for glioblastoma, a deadly form of adult brain cancer.
Center for Brain Tumor Therapy at the University of Florida, I engage continually with patients and their families in the battle against glioblastoma.
According to the American Cancer Society, about 30% of brain tumors are gliomas, a fast-growing, treatment-resistant type of tumor that includes glioblastomas, astrocytomas, oligodendrogliomas, and ependymomas.
Glioblastomas leak fluid, increasing the pressure on brain tissue; they also disrupt the blood supply, making it difficult for anti-cancer drugs to reach them.
She said that for individuals with glioblastomas, this finding identified a target for the development of a drug treatment option that currently does not exist.
Verma's team infected a small number of brain cells in mice with viruses carrying genes that reproduce alterations found in patients with glioblastoma.
Glioblastoma, the brain cancer that killed Senator Edward Kennedy, inevitably returns after tumor-removal surgery, chemotherapy, and/or radiation.
Las mutaciones del receptor del factor de crecimiento epidermico ocurren en alrededor de 50% de los glioblastomas multiformes con amplificacion de dicho receptor, lo que resulta en el EGFRVIII, una variante del receptor original, que es activado constitutivamente por continuas olas de senales.
The current investigation is believed to be the first to carefully analyze the contents of exosomes shed from glioblastoma cells and to characterize their genetic content.