glioblastoma multiforme


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glioblastoma

 [gli″o-blas-to´mah]
any malignant astrocytoma.
glioblastoma multifor´me astrocytoma grade III or IV; a rapidly growing tumor, usually of the cerebral hemispheres, composed of spongioblasts, astroblasts, and astrocytes.

gli·o·blas·to·ma mul·ti·forme

(glī'ō-blas-tō'mă mŭl'ti-fōrm),
A glioma consisting chiefly of undifferentiated anaplastic cells of astrocytic origin that show marked nuclear pleomorphism, necrosis, and vascular endothelial proliferation; frequently, tumor cells are arranged radially about an irregular focus of necrosis; these neoplasms grow rapidly, invade extensively, and occur most frequently in the cerebrum of adults.
[G. glia, glue, + blastos, germ, + -oma, tumor]

gli·o·blas·to·ma mul·ti·for·me

(glī'ō-blas-tō'mă mŭl'ti-fōr'mē)
A glioma consisting chiefly of undifferentiated anaplastic cells of glial origin that show marked nuclear pleomorphism, necrosis, and vascular endothelial proliferation; frequently, tumor cells are arranged radially about an irregular focus of necrosis; these neoplasms grow rapidly, invade extensively, and occur most frequently in the cerebrum of adults.
Synonym(s): grade IV astrocytoma.
[G. glia, glue, + blastos, germ, + -oma, tumor]
References in periodicals archive ?
How has the global glioblastoma multiforme treatment market performed so far and how will it perform in the coming years?
Yang et al., "Transmission of glioblastoma multiforme following bilateral lung transplantation from an affected donor: case study and review of the literature," Neuro-Oncology, vol.
Wu et al., "Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1," Neuro Oncology, vol.
Glioblastoma multiforme (GBM), also known as glioblastoma and grade IV astrocytoma, is the most common and most aggressive cancer that begins within the brain.
* The report provides a snapshot of the global therapeutic landscape of Glioblastoma Multiforme (GBM)
You may remember that Senator Ted Kennedy was diagnosed with glioblastoma multiforme in May 2008.
Glioblastoma multiforme is the most common and aggressive form of primary brain tumor.
However, the presence of a small number of long-term survivors, the resultant increase in clinically evident radiation-related late neurocognitive effects [8], and the promising utility of IMRT at other treatment sites justify further investigation in the management of glioblastoma multiforme. This retrospective study from our centre reports a consecutive contemporary series of patients treated with either conventionally fractionated IMRT or hypofractionated IMRT for those with poor performance status.
Glioblastoma multiforme (GBM) is the most lethal form of primary brain tumor with a dismal prognosis.
"In early December 2012, I was diagnosed with stage 4 (severely rapid and aggressive) glioblastoma multiforme [brain cancer].