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a disease of horses that is communicable to humans, caused by Pseudomonas mallei; it is marked by a purulent inflammation of the mucous membranes and an eruption of nodules on the skin that coalesce and break down, forming deep ulcers, which may end in necrosis of cartilage and bones. The more chronic and constitutional form is known as farcy.
A chronic debilitating disease of horses and other equids, as well as some members of the cat family, caused by Pseudomonas mallei and transmissible to humans. It attacks the mucous membranes of the nostrils of the horse, producing an increased and vitiated secretion and discharge of mucus, and enlargement and induration of the glands of the lower jaw. Suppurative pneumonia and skin nodules and ulcers are other forms the disease can take. Eradicated in North America and most countries; as of 1999 found only in Brazil, Mongolia and Pakistan.
[O. Fr. glandres, glands]
glanders/glan·ders/ (glan´derz) a contagious disease of horses, communicable to humans, due to Pseudomonas mallei, and marked by purulent inflammation of the mucous membranes and cutaneous eruption of nodules that coalesce and break down, forming deep ulcers, which may end in necrosis of cartilage and bone; the more chronic and constitutional form is known as farcy.
n. (used with a sing. or pl. verb)
A contagious, usually fatal disease of horses and other equids, caused by the bacterium Burkholderia mallei and characterized by swollen lymph nodes, nasal discharge, and ulcers of the respiratory tract and skin. The disease is communicable to other mammals, including humans.
Etymology: OFr, glandres, neck gland swelling
an infection caused by the bacillus Burkholderia mallei (formerly called Pseudomonas mallei), transmitted to humans from horses and other domestic animals. It is characterized by purulent inflammation of the mucous membranes and development of skin nodules that ulcerate. If untreated with antibiotics, the infection may spread to the bones, liver, central nervous system, and other tissues and cause death. It is endemic in Africa, Asia, and South America but has been eradicated in Europe and North America. Infection has been seen in laboratory workers because of the low infectious dose. It is considered a potential agent for bioterrorism.
glandersInfection by Pseudomonas mallei, a gram-negative aerobic bacillus, which affects large domestic animals, most commonly horses, and is rare in the US; human disease occurs in the form of acute, often fatal, septicemia, chronic mucocutaneous disease or pulmonary infection Clinical From cellulitis to necrosis and granulomas with draining ulcers, pleuritis, necrotizing lobar or bronchopneumonia, nasal septal necrosis, fever, chills, malaise, headaches, pustular rash, lymphadenopathy, splenomegaly; chronic disease is associated with hepatosplenomegaly, pulmonary abscess, granulomas Treatment Sulfadiazine, tetracycline, chloramphenicol, aminoglycosides. See Farcy.
glandersAn infectious disease of horses occasionally transmitted to humans. It is caused by the organism Pseudomonas mallei and features chest infection with high fever and prostration or many abscesses throughout the body, especially in the skin.
a contagious disease of all solipeds caused by Burkholderia (Pseudomonas) mallei and transmissible to humans. It occurs in a chronic or acute form, both of which are inexorably fatal. It is characterized by the development of ulcers or nodules on the skin and in the respiratory tract. In the acute form the critical lesion is bronchopneumonia. See also farcy.