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The activity of laughing; the manifestation of mirth or joy, or, less commonly, sarcasm or scorn
Alternative medicine See Laughter club, Laughter therapy, Laughter yoga
Neurology Spasmodic and largely involuntary expirations often accompanied by inarticulate vocalisations, generally evoked by mirth
Physiology Laughter increases blood flow to the brain and activates neural networks—e.g., nucleus accumbens (NAcc) and amygdala. Functional MRI data suggests that the increase in blood flow to NAcc evoked by extreme humour is similar to that triggered by monetary gain or use of some addictive drugs; a key symptom of depression is the lack of a sense of reward from previously rewarding activities—e.g., humour
Psychiatry Laughter is regarded as the most effective coping skill for anxiety-panic disorders and may temporarily alleviate the symptoms of anxiety and depression
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A series of inarticulate sounds produced as an expression of emotion, usually happiness or mirth. The role of humor and laughter in promoting a positive attitude and health and in preventing the progress of some diseases has been documented esp. when it is combined with proven medical therapies.

compulsive laughter

Laughter without cause, occurring in certain psychoses, esp. schizophrenia.

pathological laughter

Uncontrolled laughter (occasionally accompanied by, or alternating with, uncontrolled crying), caused by pseudobulbar lesions of the brain. These lesions may result from lacunar strokes, multiple sclerosis, anoxic brain injury, and other forms of brain injury.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Giggles N' Hugs is a restaurant that brings together high-end, organic food with play and entertainment for children.
Alice, who started Giggles two years ago while studying a Business Management degree at Glyndw r, said: "Although I started with weddings and children's parties, my vision for Giggles was always to move it into the corporate sector so this is almost the perfect marriage.
Building improvements, lighting fixtures and constant updating of photography equipment have cost more than $20,000 since Smith's lease was signed, and merchandise for Wee Giggles will continue to add expenses.
"Squiggles n Giggles is a business that she ought to be very proud of and which will be a valuable asset to families in North Tyneside.
"Enna would giggle for 15 minutes at a time, constantly through the day.
What better way to celebrate this special day than to seek the images of "The Heart and The Eagle" (and the chicken) and giggle and giggle!
Giggle Goodie Bag full of things to make you smile.
Giggles Baby, markets; this April marks the release of the fifth
Giggles has traditional and trendy fashions in sizes NB to 16 for girls.
Dubai Summer Surprises (DSS) visitors to the mall have already enjoyed the company of the Cylarger than lifeCO Mama, Papa, Junior and Baby Giggles who can be seen at the mall every day, providing a fantastic photo opportunity for shoppers as they entertain and amuse with their playful antics.
The BBC switchboard was said to be in "meltdown" yesterday after a newsreader collapsed in a fit of giggles in a bulletin.
The majority of the time I'm a very happy person - I'm a smiley woman who also giggles a lot.