giant cell tumours

giant cell tumours

These bone tumours usually affect young adults, causing swelling and pain in a long bone near a joint. The X ray shows a typical ‘soap bubble’ appearance. They may be BENIGN or MALIGNANT but the outlook after reasonably early surgery is usually good.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
It can be used in a variety of situations, Novartis said, including osteoporosis in postmenopausal women, during bone complications caused by cancer treatment, and giant cell tumours in the bone.
van der Geest et al., "Giant cell tumours of the small bones of the hands and feet: long-term results of 30 patients and a systematic literature review," The Bone & Joint Journal, vol.
Everolimus, the immunosuppressant drug has been used in cases of TSC involving subependymal giant cell tumours and renal angiomyolipomas.
Surgical treatment of giant cell tumours of the thoracic and lumbar spine: Report of nine patients.
The terms of malignant giant cell tumours of soft tissues, giant cell sarcoma, giant cell undifferentiated pleomorphic sarcoma and malignant osteoclastoma are synonyms used for this variant.[sup.3,4]
Giant cell tumours and intraosseous lipomas of the sacrum are both rare.
In 1972, Salm and Sissons reported a study of 10 softtissue tumors that had the histopathologic patterns of a giant cell tumor of bone; they named these masses "giant cell tumours of soft tissues." (1) In 1999, Folpe et al proposed that this entity be reclassified as a "soft tissue giant cell tumor of low malignant potential." (2) Most giant cell tumors arise in the soft tissues of the extremities, trunk, and abdomen.
Giant cell tumours of the spine (2% to 5%) typically involves only one vertebra and have a predilection for vertebral body, kyphosis secondary to body collapse may be evident on initial presentation; extension of the tumour into the epidural space may produce radicular symptoms and paraplegia.
Huang et al., "RANK and RANKL expression in giant cell tumours of the bone: an immunohistochemical study," in Proceedings of the 12th Annual Connective Tissue Oncology Society Meeting, Venice, Italy, 2006.
Giant cell tumours of tendon sheath: Classification and recurrence rate.
[4,6,8-15] Other malignant bone lesions included Ewing sarcoma, Chordoma and giant cell tumour. Giant cell tumours were more common in 3rd decade, females were commonly affected and femur was the most common site similar to other study.
Historically, giant cell tumours of lower end of radius are excised and replaced with upper end of fibula, a corticocancellous graft from tibia, iliac bone graft and acrylic prosthesis.