giant cell tumor of bone


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gi·ant cell tu·mor of bone

a soft, reddish-brown, sometimes malignant, osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells, occurring most frequently in an end of a long tubular bone of young adults.
Farlex Partner Medical Dictionary © Farlex 2012

giant cell tumor of bone

A lesion that comprises 5% of all osseous tumors, which is most common in the weight-bearing epiphysis of ♀ > age 20, which affects the distal femur, proximal tibia, distal radius; 60% recur with curettage; 10% metastasize, an event far more common in deep–to the fascial planes–tumors DiffDx A GCT-like histopathologic lesion may be seen in the brown tumor of hyperparathyroidism, chondroblastoma, giant cell reparative granuloma, benign and malignant fibrous histiocytoma, nonossifying and chondromyxoid fibroma, unicameral bone cyst, aneurysmal bone cyst, fibrous dysplasia, osteoblastoma, osteosarcoma, osteoid osteoma, eosinophilic granuloma.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

gi·ant cell tu·mor of bone

(jī'ănt sel tū'mŏr bōn)
A soft, reddish-brown, sometimes malignant, osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells, occurring most frequently in an end of a long tubular bone of young adults.
Synonym(s): giant cell myeloma, osteoclastoma.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

gi·ant cell tu·mor of bone

(jī'ănt sel tū'mŏr bōn)
A soft, reddish-brown, sometimes malignant, osteolytic tumor composed of multinucleated giant cells and ovoid or spindle-shaped cells; most frequent in young adults.
Synonym(s): osteoclastoma.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Capanna, "Curettage of giant cell tumor of bone. Introduction-material and methods," La Chirurgia degli Organi di Movimento, vol.
Results of giant cell tumor of bone treated with intralesional excision.
Giant cell tumor of bone. Curretage and cement reconstruction.
Greengard, "Critical hypercalcemia following discontinuation of denosumab therapy for metastatic giant cell tumor of bone," Pediatric Blood and Cancer, vol.
For giant cell tumor of bone, the peak incidence is in the third and the fourth decades of life for both the JST and the MC group (Figure 2).
Ghert, "High-speed burring with and without the use of surgical adjuvants in the intralesional management of giant cell tumor of bone: a systematic review and meta-analysis," Sarcoma, vol.
The nature of giant cell tumor of bone. J Cancer Res Clin Oncol.
ABC often complicates other lesions, most notably chondroblastoma, osteoblastoma and giant cell tumor of bone. The MR and CT appearances may show fluid-fluid levels, which is a nonspecific finding and can be seen in other lesions, including chondroblastoma, giant cell tumor of bone, or telangiectatic osteosarcoma.
(15,18) Primary lesions most frequently associated with ABC (in order of frequency) include giant cell tumor of bone, chondroblastoma, chondromyxoid fibroma, and fibrous dysplasia, particularly in pregnancy.
Giant cell tumor of bone is a benign, locally aggressive neoplasm with a high recurrence rate that occurs mainly in long bones of young adults.
Giant cell tumor of bone. Available on line: www.bonetumor.org/tumors/pages/page106.html.