giant cell myocarditis

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gi·ant cell my·o·car·di·tis

acute isolated myocarditis characterized by infiltration by granulomas containing giant cells.
A severe, idiopathic, possibly autoimmune-related inflammatory heart disease of young, otherwise healthy adults, which may be a virally induced immune reaction to underlying encephalitis, hepatitis, infection, intoxication, nutritional defects, thymoma, thyroiditis, Wegener’s granulomatosis, etc.
Prognosis 70% mortality
Management Heart transplant
References in periodicals archive ?
Giant cell myocarditis is a rare, progressive inflammatory myocardial disease with high mortality, affecting a relatively young population.
A clinical and histopathologic comparison of cardiac sarcoidosis and idiopathic giant cell myocarditis.
Cardiac transplantation for pediatric giant cell myocarditis.
A novel experimental model of giant cell myocarditis induced in rats by immunization with cardiac myosin fraction.
Successful treatment of severe heart failure caused by idiopathic giant cell myocarditis.
Recovery from giant cell myocarditis with ECMO support and utilisation of polyclonal antithymocyte globulin: a case report.
Recurrence of giant cell myocarditis in cardiac allograft.

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