giant cell myocarditis


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gi·ant cell my·o·car·di·tis

acute isolated myocarditis characterized by infiltration by granulomas containing giant cells.
A severe, idiopathic, possibly autoimmune-related inflammatory heart disease of young, otherwise healthy adults, which may be a virally induced immune reaction to underlying encephalitis, hepatitis, infection, intoxication, nutritional defects, thymoma, thyroiditis, Wegener’s granulomatosis, etc.
Prognosis 70% mortality
Management Heart transplant
References in periodicals archive ?
(4) Giant cell myocarditis does, however, recur in approximately 25% of transplanted hearts.
Giant cell myocarditis is a rare, progressive inflammatory myocardial disease with high mortality, affecting a relatively young population.
Giant cell myocarditis: clinical and pathological disease characteristics in an Indian population.
Cardiac transplantation for pediatric giant cell myocarditis. J Heart Lung Transplant.
Giant cell myocarditis: most fatal of autoimmune diseases.
A case of giant cell myocarditis: bridge to recovery by long-term mechanical circulatory support without immunosuppressive therapy.
Recurrence of giant cell myocarditis in cardiac allograft.

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