giant cell hyaline angiopathy

gi·ant cell hy·a·line an·gi·op·a·thy

an inflammatory infiltrate containing foreign body giant cells and eosinophilic material. Fragments of foreign material resembling vegetable matter may be included.
Synonym(s): pulse granuloma

gi·ant cell hy·a·line an·gi·op·a·thy

(jīănt sel hīă-lin anjē-opă-thē)
Inflammatory infiltrate containing foreign body giant cells and eosinophilic material.
References in periodicals archive ?
Pulse granuloma is a rare benign entity that has also been called oral vegetable granuloma[1] and giant cell hyaline angiopathy.[2] Most of the literature suggests that the pathogenesis is a foreign body reaction to ingested legume parenchymatous cells at various stages of digestion.[1,3-7] Vegetable particles have been demonstrated associated with granulomas and hyaline rings in most of the reported cases in the literature[4,5,8-10] and in 2 reviews of a larger number of cases.[3,6] The histologic and ultrastructural findings of a series of cases of pulse granulomas have also been reported.[1] Animal experiments with injection of vegetable matter in lungs and oral cavity have demonstrated reactions similar to lentil granulomas observed in humans.[3,7]
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