giant cell hepatitis
hepatitis in the neonatal period presumed to be due to any of a variety of causes, chiefly viral; characterized by direct and indirect bilirubinemia, hepatocellular degeneration, and appearance of multinucleated giant cells; may be difficult to distinguish from biliary atresia, but is more likely to end with recovery, although cirrhosis may develop.
Synonym(s): giant cell hepatitis
Farlex Partner Medical Dictionary © Farlex 2012
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
giant cell hepatitisGiant cell transformation of liver Neonatology A nonspecific reaction of the newborn liver to ↑ conjugated hyperbilirubinemia; conjugated BR is ↑ in infants with intra- or extrahepatic biliary atresia, erythroblastosis fetalis, TORCH–toxoplasmosis, rubella, CMV, HS, and other in utero and neonatal infections–eg, coxsackie, hepatitis, E coli, syphilis, metabolic defects–eg, α1-antitrypsin deficiency, cystic fibrosis, hereditary fructose intolerance, galactosemia, parenteral nutrition and tyrosinosis, choledocal cysts, idiopathic, congenital hepatic fibrosis, Byler's disease, Lucy-Driscoll disease, Niemann-Pick disease, trisomy 18, and Zellweger's disease. Cf Syncytial giant cell hepatitis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.