giant cell fibroma


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gi·ant cell fi·bro·ma

a tumor of the oral mucosa composed of fibrous connective tissue with large stellate and multinucleate fibroblasts; shares a similar histology with the retrocuspid papilla, fibrous papule of the nose, pearly penile papule, and the ungual fibroma.
Farlex Partner Medical Dictionary © Farlex 2012
The oral counterpart of fibrous papule of the nose, which appears as an asymptomatic sessile or pedunculated nodule measuring less than 1 cm in diameter. Often, it has a bosselated or somewhat papillary surface. Most cases occur in ages 10-30 years. No sex predilection has been reported. The most common sites are the mandibular gingiva, followed by maxillary gingiva, tongue and palate.
DiffDx Squamous papilloma, irritation fibroma, pyogenic granuloma, and peripheral giant cell granuloma
Management Conservative excisional biopsy is curative, and its findings are diagnostic. Recurrence is rare
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

gi·ant cell fi·bro·ma

(jī'ănt sel fī-brō'mă)
A tumor of the oral mucosa composed of fibrous connective tissue with large stellate and multinucleate fibroblasts.
Compare: giant cell granuloma
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

gi·ant cell fi·bro·ma

(jī'ănt sel fī-brō'mă)
Tumor of oral mucosa composed of fibrous connective tissue with large stellate and multinucleate fibroblasts.
Medical Dictionary for the Dental Professions © Farlex 2012
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Since the lesion presented as a firm painless well-circumscribed swelling in the anterior gingiva and additionally the patient had a fair Silness and Loe plaque index, reactive lesions due to chronic low-grade irritation (dental plaque and food impaction) like peripheral ossifying fibroma, healing pyogenic granuloma, peripheral giant cell granuloma, and giant cell fibroma were considered as differential diagnoses.
PCNA and Ki-67 immunoreactivity in multinucleated cells of giant cell fibroma and peripheral giant cell granuloma.
The differential diagnosis consisted of pyogenic granuloma, periapical giant cell granuloma, aggressive gingival fibromatoses, odontogenic myxoma, periapical odontogenic fibroma, and giant cell fibroma. These outcomes were discussed with the patient in an attempt to alleviate fear of carcinoma.
INTRODUCTION: The localized lesions of the oral cavity have been broadly documented as: Irritation fibroma, Peripheral ossifying fibroma, squamous papilloma, Giant cell fibroma, Pyogenic granuloma and Peripheral giant cell granuloma.