gestrinone


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gestrinone

A testosterone-like drug that interferes with the release of GONADOTROPHIC HORMONES and can be used in women to treat ENDOMETRIOSIS. A brand name is Dimetriose.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Etiocolanolone, Epimetendiol, Drostanolone, Metandrolone, Danazol, Androsterone, Nandrosterone, Methandienone, Methyltestosterone, Oxandrolone, Gestrinone, Epitrenbolone, Mesterolone and Methenolone constituted 4.11% of the AAF altogether.
Gestrinone, another drug used for emergency contraception, has been shown to cause subjective hoarseness when used for at least 6 months for the indication of endometriosis and uterine leiomyoma.
It was pointed out that the prevention measures for the recurrence of endometrial polyp were diversified, including progesterone hormone preparations, short-acting contraceptives, gestrinone, gonadotrophin releasing hormone, traditional Chinese medicines and intrauterine devices containing sustained-release drugs.17
(34) Standard management utilises non-steroidal anti-inflammatory drugs (NSAIDs) and analgesics to reduce pain, hormonal drugs including oral contraceptives, danazol, gestrinone, GnRH agonists, and dienogest to suppress ovarian function, and laparoscopy to ablate endometriotic lesions.
Patients in the treatment group were treated with BSHXP (Table 3), while patients in the control group were administered with Western medicine, including mifepristone, Diphereline, gestrinone, and danazol.
Exogenous: 1-androstendiol, 1-androstendione, bolandiol, bolasterone, boldenone, boldione, calusterone, clostebol, danazol, dehydrochlormethyltestosterone, desoxymethyltestosterone, drostanolone, ethylestrenol, fluoxymesterone, formebolone, furazabol, gestrinone, 4-hydroxytestosterone, mestanolone, mesterolone, metenolone, methandienone, methandriol, methasterone, methyldienolone, methyl-1-testosterone, methylnortestosterone, methyltrienolone, methyltestosterone, mibolerone, nandrolone, 19-norandrostenedione, norboletone, norclostebol, norethandrolone, oxabolone, oxandrolone, oxymesterone, oxymetholone, prostanozol, quinbolone, tanozolol, stenbolone, 1-testosterone, tetrahydrogestrinone, trenbolone
(13) One Chinese trial found that the anti-progestin gestrinone was as effective as 10 mg mifepristone.
Interesting results have been obtained with the introduction of gestrinone, a steroid with androgenic, antiprogestinic and antioestrogenic activities.
Gestrinone, a medication most commonly used to treat endometriosis, is as effective an emergency contraceptive method as mifepristone, according to a study of women at five Chinese clinics who sought emergency contraception within 72 hours of an act of unprotected inter-course.
Discovery, biosynthesis, and structure elucidation of metabolites of a doping agent and a direct analogue, tetrahydrogestrinone and gestrinone, using human hepatocytes.
Gestrinone is a 19-notestosterone derivative with antiprogestinic, anti-oestrogenic and androgenic effects.
In one trial, Chinese herbal medicine provided symptomatic relief comparable to that provided by the hormonal drug gestrinone, but with fewer side effects.

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