germfree


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germfree

(jûrm′frē′)
adj.
Free of microorganisms.

gnotobiotic

Biology
adjective Referring to a system to which only preselected components, organisms and nutrients are introduced. Gnotobiotic organisms are either experimental models (e.g., mice with naïve immune systems), or “experiments of nature”, in which the natural immune defence is grossly defective (e.g., severe combined immune deficiency); prolonged survival of the host requires complete avoidance of exposure to pathogens.
References in periodicals archive ?
If the microbiota effect was largely mediated by TLR signalling, it was expected to discover similar expression patterns in germfree and [MyD88.sup.-/-] mice.
Mutants of Streptococcus suis types 1 and 2 impaired in expression of muramidase-released protein and extracellular protein induce disease in newborn germfree pigs.
The Vicks GermFree Warm Mist humidifier features a dual-action ultraviolet light and boiling system that kills up to 99.9% of bacteria, molds and spores in the moisture it expels into the room, according to the company.
For example, the villi of the small intestine are longer; crypts are shorter and contain fewer cells in germfree mice than in age-matched conventional animals (39).
grew but did not cause diarrhea in streptomycin-treated mice and germfree chickens (Almeida and Nunes, 1996; Graf, 1999).
The process uses only water, heat and a patented technology to produce a clean, germfree surface without chemicals.
(17.) X-Ray Spex, Germfree Adolescents, Caroline Records, CAROL 1813-2.
The recipient left a germfree room in an intensive care unit for a normal hospital room on Thursday last week.
In place of their old bathrooms, with their wood-encased fixtures, ornate wall decorations and fancy rugs that served as breeding grounds for germs, the rich installed new ones equipped with white china fixtures, white tiled walls and white toilets - deemed much easier to keep germfree. As one physician noted in 1884:
Our national obsession with creating a germfree environment could result in a public health crisis as the use of antimicrobial agents becomes more widespread."
Well, he had created a germfree environment, anyway; after him others would surely be able to introduce many more improvements, but he had at least proved there was a different way.