gnotobiotic

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gno·to·bi·ot·ic

(nō'tō-bī-ot'ik),

Denoting germ-free or formerly germ-free organisms in which the composition of any associated microbial flora, if present, is fully defined.

[see gnotobiota]

gnotobiotic

[nō′tōbī·ot′ik]

pertaining to a germ-free animal or an animal or an environment in which all the microorganisms are known. See also germ-free animal.

gnotobiotic

Biology
adjective Referring to a system to which only preselected components, organisms and nutrients are introduced. Gnotobiotic organisms are either experimental models (e.g., mice with naïve immune systems), or “experiments of nature”, in which the natural immune defence is grossly defective (e.g., severe combined immune deficiency); prolonged survival of the host requires complete avoidance of exposure to pathogens.

gno·to·bi·ot·ic

(nō'tō-bī-ot'ik)

Denoting germ-free or formerly germ-free organisms in which the composition of any associated microbial flora, if present, is fully defined.

gnotobiotic

literally ‘known life’; typically referring to an environment or animal that is essentially germ-(microorganism-) free, or one in which the microbial flora present is known, usually because it has been deliberately introduced.

gnotobiotic

pertaining to a gnotobiote or to gnotobiotics.

gnotobiotic animal

one that has been born germ free and then infected with known microorganisms. See also axenic and specific pathogen free.

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References in periodicals archive ?

Using molecular marker analysis, Surh and colleagues found that antigen-free mice were depleted of Tregs in the small intestine whereas a large number of these Tregs were present in germ-free counterparts fed a "normal" protein diet.

Why Children More Likely to Develop Food Allergies

sup][4],[5] Experiments in germ-free mice demonstrated that gut microbiota plays a role in clearing the pathogenic bacterium Citrobacter rodentium and the clearance was found to be mediated by the enhanced glycan acquisition capabilities of the transferred bacteria.

Commensal Microbiome Promotes Resistance to Local and Systemic Infections

Fireman Sam loving ve-year-old Seth Lane is undergoing treatment in the hospital's sterile, germ-free Bubble Unit while he awaits an operation that doctors hope will kick start his immune system.

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The company said this Denver office's first order of business will be to finalise a new product-testing deal that will allow NTRR and S2O2 to demonstrate the efficacy of their non-toxic, antimicrobial coatings in the germ-free and pest-free cultivation of medical-grade cannabis.

Neutra Corp's partner expands into Denver, Colorado

But if you want to aim for germ-free, go with fist bumps instead.

A less germy hello

When they transferred gut bacteria that had been mixed with saccharin (in a test tube) to germ-free mice, the animals' glucose tolerance got worse.

Sweet confusion

Plant factories grow vegetables in close to sterile conditions in almost germ-free cleanrooms.

Toshiba produces vegetables in factory

Through our newest line of top loaders which use heaters to clean the clothes and the tub itself, we are making it possible for our consumers to not just have clean clothes, but sterile and germ-free as well.

LG amps up hygiene offers with new washers

The water generated by the condensation is microbiologically pure since it is first sterilised with an ozone process and then further made germ-free through two different UV process, before the mineralisation and before being served.

Drinking water for life

The study revealed that germ-free mice are more susceptible to infection with the foodborne pathogen Listeria monocytogenes than mice with conventional intestinal microbiota.

Thank germs in your gut for keeping you healthy

Municipal Services and other relevant departments utilised all of their resources to keep the city clean and germ-free during these works, Soomro said on completion of the operation on the third day of Eid-ul-Azha, said a press release on Friday.

More than a million offal disposed of by KMC, DMCs: Saqib Soomro

RATING: 3/5 Orla Kiely Geranium Hand Sanitiser, PS5 for 50ml (John Lewis) THE geranium essential oil scent is instantly uplifting when applied for germ-free hands.