A unifying link to many of these associations is the notion that testicular germ cell
tumors originate in maldeveloped testes with impaired Sertoli cell function.
Germ-cell tumours occur when cancer develops from germ cells
outside of the ovaries or testicles.
In terms of classification, there were 268(63.8%) surface epithelial-stromal tumours, 100 (23.8%) germ cell
tumours, 29(6.9%) sex cord-stromal tumours, 12(2.9%) metastatic tumours, and11(2.6%) miscellaneous tumours.
At 13.5 days post coitum, germ cells
accumulated at the gonadal regions of the embryonic urogenital ridges.
This gene is located in the 12q21.3.2 chromosomal region and is responsible for primordial germ cell
development, survival, and migration.
The H3K4me3 ChIP-Seq data of chicken follicular mesenchymal cells and male germ cells
were acquired, and we also included H3K27me3 ChIP-Seq data of chicken germ cells
to demonstrate the effect of bivalent H3K4me3/H3K27me3 on gene transcription.
Graziana et al., "Dendritic cell infiltration in a patient with seminomatous germ cell
tumor of the testis: is there a relationship with infertility and tumor stage?," Journal of Urology, vol.
Norgaard-Pedersen, "Alpha-feto-protein (AFP) and human chorionic gonadotropin (hCG) as biochemical markers of intracranial germ cell
tumours," Acta Neurochirurgica, vol.
Birch, "Comparative incidence patterns and trends of gonadal and extragonadal germ cell
tumors in England, 1979 to 2003," Cancer, vol.
Kramar et al., "Early predicted time to normalization of tumor markers predicts outcome in poorprognosis nonseminomatous germ cell
tumors," Journal of Clinical Oncology, vol.
In order to evaluate the cell differentiation into male germ cells
, immunocytochemistry was used to detect Mvh and Scp3 germ cell
Benign Cystic Teratoma is the most common germ cell
tumours that tend to be grossly and microscopically distinctive, as they contain skin and skin appendages as well as benign tissues derived from other germ cell