53] tumor suppressor gene, which is known to be implicated in cancer development, has been investigated as a possible biomarker for genotoxin
in fish cells .
Neither of these solvents is considered a genotoxin
or a carcinogen; the weight of evidence from human in vivo studies suggests that exposure to toluene does not cause somatic cell genotoxic damage (7), although this view has been questioned by recent studies of rotogravure printers (8,9).
In addition to bacterial assays, MX is a direct-acting mutagen and genotoxin
in vivo (17-21) and in mammalian cells in vitro (21-27).
Transplacental transfer of genotoxins
and transplacental carcinogenesis.
Blair, "Vitamin C-induced decomposition of lipid hydroperoxides to endogenous genotoxins
," Science, vol.
Since presence of genotoxins
in the aquatic environment is a well-known fact, attempt to develop sensitive biomarkers to evaluate genotoxic effects in aquatic organisms has gained importance.
Potentially harmful constituents have been documented in some e-cigarette cartridges, including diethylene glycol, genotoxins
and animal carcinogen," it added.
Potentially harmful constituents also have been documented in some e-cigarette cartridges, including irritants, genotoxins
, and animal carcinogens (1).
Comparative study of the sensitivities of onion and broad bean root tip meristematic cells to genotoxins
BlueScreen HC uses Gaussia luciferase to detect the up-regulation of a key reporter gene, GADD-45a, in response to genotoxic stress and can detect all known classes of genotoxins
Nevertheless in the study cited above (1) the intensity of exposure to genotoxins
from polluted air was able to induce chromosomal damage more efficiently than tobacco smoke.
Use of plant bioassays for the detection of genotoxins
in the aquatic environment.