Among the different types of exposures to a
genotoxic compound, occupational exposure is very important, as the individual is continuously and directly in contact with the compound.
IPCS guidelines for the monitoring of
genotoxic effects of carcinogens in humans.
cordifolia as alternative source of natural compounds to cure
genotoxic - related problems.
With respect to the results listed in Table 2, the orange and grape juices of the five food companies, at both exposure times considered, induced significant formation of mitotic spindle changes, represented in this study by colchicine metaphase and anaphase and telophase bridges, proving to be
genotoxic, and chromosome breaks, characterized by the formation of micronuclei.
Genotoxic effect of metals on freshwater mussels is very important to assess the aquatic health and could be suggested as biomarker.
Accordingly, ZnO nanorods
genotoxic evaluation administered orally in Swiss mice for a 7 day period with the lowest possible inevitable exposure doses was aimed.
This study also concluded that comet bioassay can be used for in-vivo experiments, using fish as a model for the screening of
genotoxic and mutagenic pollutants in aquatic environment.
Cells exposed to a
genotoxic environment may act in different manners.
The studies related to the impact of
genotoxic exposure in an organism, therefore, not only cover an attempt to elucidate the mechanism(s) involving direct changes to the genetic material, but also the
genotoxic effects and changes at the level of gene pool and population [3].
5] and evidence supporting that a
genotoxic mode of action is still insufficient [5].
1) Based on this strong evidence, it would be useful to know if and to what extent radiotherapy causes
genotoxic and cytotoxic effects resulting in DNA damage on oral mucosa.
In addition, occupational exposure to pesticides poses major threats including adverse reproduction, congenital anomalies and
genotoxic effects (Hussain et al.
