genotoxic


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Related to genotoxic: genotoxic carcinogen

genotoxic

 [je´no-tok″sik]
damaging to DNA; pertaining to agents (radiation or chemical substances) known to damage DNA, thereby causing mutations or cancer.

ge·no·tox·ic

(jē'nō-toks'ik),
Denoting a substance that by damaging DNA may cause mutation or cancer.
[gene + toxic]

genotoxic

/ge·no·tox·ic/ (je´no-tok″sik) damaging to DNA: pertaining to agents known to damage DNA, thereby causing mutations, which can result in cancer.

genotoxic

[jē′nōtok′sik]
capable of altering DNA, thereby causing cancer or mutation.

genotoxic

adjective Referring to a factor or substance that causes chromosomal or DNA damage.

ge·no·tox·ic

(jē'nō-toks'ik)
Denoting a substance that by damaging DNA may cause mutation or cancer.
References in periodicals archive ?
Among the different types of exposures to a genotoxic compound, occupational exposure is very important, as the individual is continuously and directly in contact with the compound.
cordifolia as alternative source of natural compounds to cure genotoxic - related problems.
With respect to the results listed in Table 2, the orange and grape juices of the five food companies, at both exposure times considered, induced significant formation of mitotic spindle changes, represented in this study by colchicine metaphase and anaphase and telophase bridges, proving to be genotoxic, and chromosome breaks, characterized by the formation of micronuclei.
Genotoxic effect of metals on freshwater mussels is very important to assess the aquatic health and could be suggested as biomarker.
Accordingly, ZnO nanorods genotoxic evaluation administered orally in Swiss mice for a 7 day period with the lowest possible inevitable exposure doses was aimed.
This study also concluded that comet bioassay can be used for in-vivo experiments, using fish as a model for the screening of genotoxic and mutagenic pollutants in aquatic environment.
Cells exposed to a genotoxic environment may act in different manners.
The studies related to the impact of genotoxic exposure in an organism, therefore, not only cover an attempt to elucidate the mechanism(s) involving direct changes to the genetic material, but also the genotoxic effects and changes at the level of gene pool and population [3].
1) Based on this strong evidence, it would be useful to know if and to what extent radiotherapy causes genotoxic and cytotoxic effects resulting in DNA damage on oral mucosa.
In addition, occupational exposure to pesticides poses major threats including adverse reproduction, congenital anomalies and genotoxic effects (Hussain et al.