The authors analysed survey responses and performed genome-wide
association studies (GWAS) on data from more than 477,522 people in databases UK Biobank, and 23andMe.
The paper, T-Scan: A Genome-wide
Method for the Systematic Discovery of T Cell Epitopes, was published online in the Journal Cell by Tomasz Kula, Mohammad H.
Then they did a genome-wide
association study of bitter and sweet beverage consumption, before confirming the key findings in three US cohorts.
association studies (GWAS), using the chips, makes it possible to detect the genetic variants underlying the traits of interest.
association mapping, commercial varieties/lines can be used for mapping purposes.
"However, this is the first paper with the largest genome-wide
mega-analysis involving 15,212 individuals with epilepsy and 29,677 healthy individuals," he added.
Researchers at the UC San Francisco and Washington University School of Medicine, analysed genome-wide
data from over 1.5 million individuals, making it one of the largest-ever studies of Alzheimer's genetics.
association study of varicose veins was also performed among 337,536 unrelated individuals (9,577 cases) of white British descent.
In the study, researchers looked at height and BMI differences in 9, 416 people from 14 European countries and used data from genome-wide
"The algorithm outperforms state-of-theart methods for genome-wide
gene regulatory network inference by incorporating prior biological knowledge and regularisation to prune false positives," said Dr Mall.
association studies (GWAS) have revealed dozens of single nucleotide polymorphisms (SNPs) associated with a cognitive performance in SZ or AD patients, as well as in normal healthy subjects [5-10].