genistein


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genistein

(jə-nĭs′tē-ĭn, -tēn′)
n.
A phytoestrogen of the isoflavone class that is found in soybeans and certain other plants.

genistein

(jĕ-nĭs′tēn, tē-ĭn)
A soy isoflavone that has been found to inhibit the activity of enzymes involved in the control of cell proliferation. It is a phytoestrogen with weak estrogenic and anti-estrogenic effects.
References in periodicals archive ?
Evaluation of genistein mediated growth, metabolic and anti-inflammatory responses in broilers.
developed a useful protocol based on MSDP coupled to LC for the determination of daidzein and genistein in soybeans [19], obtaining high extraction efficiencies (greater than 80%) regardless of the use of lower amounts of sample and solvents than traditional methods.
In this study, we provide an assessment of the effects of a genistein diet upon jejunum motility and contractility, jejunum wall thickness, and a quantification of acetylcholine receptors (AChR) in ob/ob mouse jejunum.
The present study aimed (i) to detect the presence of cinnamic acid derivatives and genistein in the germinated and ungerminated seed extracts of two species of Lupinus, L.
Our most recent study demonstrated that genistein could normalize DEHP induced neonatal effects through antioxidative action, which also revealed coadministration of the two EDCs did not follow classical dose-response effects and highlighted the importance of assessing impacts across a range of doses and ages [13].
Resveratrol has been reported to extend lifespan in animal studies and it's been suggested genistein could play a role in the prevention of some cancers, including breast cancer.
The growth of both estrogen-dependent and estrogen-independent breast cancer cells has been inhibited by genistein. It is reported that women who ate more than 15 grams of soybean protein per day had a 30% lower risk of recurrence compared to women who ate less than 5 grams of soybean protein per day.
In most experimental studies, where the association of soy isoflavones and breast cancer risk has been investigated, a single component, e.g., genistein or daidzein was employed (9).
Research conducted by the team, described in 1996 in Clinical & Experimental Metastasis and in Molecular Pharmacology in 1997, demonstrated that genistein dose-dependently inhibited human prostate cancer cell detachment, which is due to the isoflavone's ability to increase cell adhesion.
The drugs trial aims to find out whether high doses of the treatment Genistein Aglycone is effective in people with Sanfilippo disease.