genetic signature

genetic signature

A pattern of specific, detectable nucleic acids that identify a particular cell, tissue, disease, or malignancy.
References in periodicals archive ?
Just planting the seeds of a tree doesn't guarantee the genetic signature of the tree will be saved.
In a new study, published online by Clinical Cancer Research, scientists from the Dana-Farber Cancer Institute have found a genetic signature within prostate cancer cells that they say can predict which tumors are likely to metastasize.
By performing deep gene sequencing on members of a family from Northern France with EPP of a previously unknown genetic signature, Paw's team discovered a novel mutation of the gene CLPX, which plays a role in mitochondrial protein folding.
Researchers observed that the lab-grown liver buds have molecular and genetic signature profiles that very closely resemble those found in naturally developing human liver cells.
The results suggest that clinical trials now need to look at cancer patients who share the same genetic signature in their cancer.
The goal is to use the cat's genetic signature to help determine the disease's cause and novel therapies for treatment.
For example, research by the US Agency for International Development (USAID) found that epidermolysis bullosa, a debilitating inherited skin disorder, has a different genetic signature in patients from the Middle East than in those from other parts of the world.
The young are a population who need this kind of extra testing, turning over every rock to find that hidden genetic signature, which may be something you've heard of or something that you haven't," said Geoff Oxnard, an assistant professor of medicine at the Dana-Farber Cancer Institute and Harvard Medical School.
Only when Caine (Channing Tatum), a genetically engineered ex-military hunter, arrives on Earth to track her down does Jupiter begin to glimpse the fate that has been waiting for her all along--her genetic signature marks her as next in line for an extraordinary inheritance that could alter the balance of the cosmos.
University College London's Professor Martin Widschewndter said: "We identified a genetic signature in women with a mutated gene linked to increased cancer risk.
The genetic signature is thought to have arisen among people living in Beringia, researchers said.
Cancers can be categorised according to their site, their stage and grade; in the future we may be able to identify cancers according to their genetic signature, or the range of mutated genes within their DNA.