genetic heterogeneity


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Related to genetic heterogeneity: Incomplete penetrance

ge·net·ic het·er·o·ge·ne·i·ty

the character of a phenotype produced by mutation at more than one gene or by more than one genetic mechanism. See: genocopy.
References in periodicals archive ?
Tibiletti, "Genetic heterogeneity in HER2 testing may influence therapy eligibility," Breast Cancer Research and Treatment, vol.
Genetic heterogeneity: cancer cells harboring genetic mutations that lead to mTORC1 overactivation coexist with cancer cells displaying low mTORC1 activity.
[20] Tso-Ren Wang and Shio-Jean Lin, "Further evidence for genetic heterogeneity of whistling face or Freeman-Sheldon syndrome in a Chinese family," American Journal of Medical Genetics, vol.
Genetic heterogeneity and gene diversity in the population of Punjab, Pakistan, based on AB0 and Rh(D) blood group frequencies.
In the Atlantic, no genetic heterogeneity has been detected over widespread areas for blue marlin (Makaira nigricans) (McDowell et al., 2007), sailfish (Istiophorus platypterus) (Graves and McDowell, 2003), and wahoo (Garber et al., 2005).
Bisceglia, L., Cerullo, G., Forabosco, P., Genetic heterogeneity in Italian Families with IgA nephropathy suggestive linkage for two novel IgA nephropathy loci.
Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus.
Nevertheless, grouping analysis employing the genetic distance method of Nei did not correlate genetic heterogeneity of species and populations with geographical areas.
They addressed some factors contributing to it, namely different racial and environmental factors as well as genetic heterogeneity between Asian and Caucasian populations.
Interspecific genetic heterogeneity of wild and domesticated Ocimum genus in Brazil conducted using RAPD markers demonstrated that wild varieties had lowest within-species similarity indices [10].
In conclusion, our observation suggests that SENsyndromeshouldberecognizedasanentity with genetic heterogeneity once there is evidence of different genetic manner of inheritance described in this disease.
They cover the evolution of understanding its clinical and genetic heterogeneity and molecular and biochemical basis; its clinical and genetic classification and epidemiology; research on the condition; bone biology, structure, and biochemistry; its clinical and molecular genetics; key mutations; animal models; brittle bone overlap phenotypes; clinical aspects, including differential diagnosis; organ involvement; orthopedics; physical medicine and rehabilitation; pharmacologic treatment; and the genetic approach to treatment.