genetic determinant


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ge·net·ic de·ter·mi·nant

any antigenic determinant or identifying characteristic, particularly those of allotypes.
Synonym(s): genetic marker

ge·net·ic de·ter·mi·nant

(jĕ-net'ik dĕ-tĕr'mi-nănt)
Any antigenic determinant or identifying characteristic, particularly those of allotypes.

ge·net·ic de·ter·mi·nant

(jĕ-net'ik dĕ-tĕr'mi-nănt)
Any antigenic identifying characteristic.
References in periodicals archive ?
GlobalData epidemiologists attribute the projected increase in the lifetime prevalent cases of asthma across all the markets covered in this analysis to changing population demographics in the respective markets, except for the US and the UK, where this growth is also attributed to trends in genetic determinants, social status, environmental factors, and changes in policies related to disease identification and recording (Simpson and Sheikh, 2010; Smith et al., 2005).
Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study.
Cellular, molecular, and genetic determinants of tooth eruption.
This may in fact be associated with environmental exposures as the authors have hypothesized, but may also be related to genetic determinants. Further studies may help define these differences, especially for the province of Quebec, where there seems to be a higher prevalence than reported in the literature.
A number of genetic association studies examined SNPs as these are considered as the primary genetic determinants of the inter-individual variability in susceptibility to disease, response to treatment (pharmacogenetics) and clinical outcomes (7-9).
Specialists in endocrinology, pediatrics, and other medical fields from Europe, North America, and Israel discuss historical, sociocultural, biochemical, metabolic, neuroendocrinologic, and genetic determinants; environmental factors; short and long-term complications like diabetes, dyslipidemia, fatty liver disease, hypertension and renal disease, sleep-disordered breathing, and cardiovascular disease; the effects of lifestyle counseling, pharmacotherapy, and surgical interventions; and the roles of globalization and government policy.
So it is reasonable to suggest that pretreatment status of telomerase expression level apart from karyotype abnormalities, could be considered as novel genetic determinants of prognosis and could be utilized in the routine work up of MDS and ANLL patients at diagnosis.
And yet other tests for genetic determinants of treatment response and the likelihood of treatment-related adverse events show promise but remain largely in the realm of research, said Dr.
"This unique collaboration has allowed us to discover novel genetic determinants of blood cell parameters, providing important insights into novel biological mechanisms underlying the formation of blood cells by the blood stem cells and their role in disease," Soranzo added."This study highlights the importance of studying large collections of samples from healthy individuals where many different traits are measured," Soranzo noted.The team compared regions of the human genome implicated in blood cell development with regions associated with risk of heart disease.