generalized transduction

generalized transduction

TRANSDUCTION in which any region of the donor GENOME, of appropriate size, could be mistakenly packaged in the BACTERIOPHAGE. Thus all possible NUCLEOTIDE SEQUENCES of the donor BACTERIUM could be represented in the population of transducing particles. Upon transfer to the recipient a transduced chromosomal fragment may recombine with the HOMOLOGOUS REGION of the resident CHROMOSOME. Transduced PLASMIDS may exist as EXTRACHROMOSOMAL DNA in the recipient. Recipients carrying the transduced DNA are called transductants. The process has been used in fine structure genetic mapping of chromosomes. Compare SPECIALIZED TRANSDUCTION.
References in periodicals archive ?
A sampling of topics from the first volume: bacteriophage enrichment from water and soil, isolation of phage via induction of lysogens, enumeration of bacteriophages by double agar overlay plaque assay, basic phage electron microscopy, construction of phage mutants, generalized transduction, and preparation and characterization of anti-phage serum.
Although generalized transduction is rare, critics question the safety of ingesting these bacteriophages along with genetically engineered food products.
These include phages carrying genes linked to specialized transduction (8) and genes likely linked to generalized transduction (9).
Mutability in escherichia coli K12 enhanced by a P1-plasmid and by generalized transduction. Rivista di Biologia/Biology Forum, 76(3), 493-499.

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