general paresis

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 [pah-re´sis, par´ĕ-sis]
slight or incomplete paralysis. adj., adj paret´ic.
general paresis chronic meningoencephalitis from a syphilitic infection that is causing gradual loss of cortical function, resulting in progressive dementia and generalized paralysis; this may occur 10 to 20 years after an initial infection of syphilis in untreated individuals. Called also Bayle's disease and dementia paralytica.

pa·ret·ic neu·ro·syph·i·lis

a type of later tertiary syphilis, clinically manifested by progressive dementia (often with delusional systems), seizures, Argyll-Robertson pupils, dysarthria, myoclonic jerks, action tremors, generalized hyperreflexia, and Babinski signs; pathologic studies reveal a chronic frontotemporoparietal meningoencephalitis; formerly one of the major causes for insanity.

general paresis

Dementia and progressive muscular weakness leading to paralysis, occurring as a late consequence of syphilis.

general paresis

Etymology: L, genus, kind; Gk, paralysis
a neurological disorder that results from chronic syphilitic infection. It is characterized by degeneration of the cortical neurons; progressive dementia, tremor, and speech disturbances; muscular weakness; and ultimately generalized paralysis. It is often accompanied by periods of exultation and delusions of grandeur. Treatment usually consists of large doses of penicillin, without which the outcomes are almost invariably progressive deterioration and death. Also called paretic dementia, syphilitic meningoencephalitis.

general paresis

Neurology A symptom of late tertiary syphilis 10+ yrs after the initial infection, caused by chronic meningoencephalitis resulting in progressive dementia and generalized paralysis. See Syphilis.

general paresis


General paresis

A form of neurosyphilis in which the patient's personality, as well as his or her control of movement, is affected. The patient may develop convulsions or partial paralysis.
Mentioned in: Syphilis
References in periodicals archive ?
that general paresis is due to the spirochete of syphilis, that Alzheimer's disease is associated with neurofibrillary tangles in the brain, or that lead drove the hatter mad.

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