gene suppression


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gene suppression

The situation in which a normal PHENOTYPE develops in an individual or cell with a mutant gene due to a second mutation either in the same gene or in a different gene.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
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There is an introduction to technologies for gene suppression as well as molecular diagnostics to detect and monitor gene expression.
A battery of different tests conducted on rat livers found that sunflower oil induced fibrosis, gene suppression and high levels of oxidation.
Many reports have demonstrated that introduction of siRNAs into mammalian cells may lead to unintended gene suppression via RNAi-independent and/or RNAi-mediated mechanisms.
Cilation: "Increase developmental plasticity of human keratinocytes with gene suppression;" Shengwen Calvin Li, et al.; Proceedings of the National Academy of Sciences, 18 July 2011, DOI: 10.1073/pnas.1100509108
The hypothesis was that the gene suppression would act like a clogged pipe, creating an abundance of compounds that would have later become phenylalanine in a normal plant.