gene repression


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gene repression

the deactivation of an active gene that causes a shut-down of TRANSCRIPTION. see OPERON MODEL.
References in periodicals archive ?
Horlbeck, "Compact and highly active next- generation libraries for CRISPR-mediated gene repression and activation," 9, vol.
SUV39-h1 and SUV39-h2 histone methyltransferases that catalyze methylation of H3K9 [9], G9a [29], and EZH2 [30] are responsible for methylation of H3K27, whereas methylation on histones H3K9 and H3K27 is usually associated with gene repression.
It is suggested that the methylation of H3K27 is associated with gene repression [42].
Histone methylation could be manifested as gene repression or activation depending upon the residue modified [53].
Innate gene repression associated with Mycobacterium bovis infection in cattle: toward a gene signature of disease.
"It was surprising to see that two proteins that have always been associated with gene repression through DNA methylation are activated in the most transcriptionally active regions of stem cells.