gene mapping


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ge·net·ic map

an abstract representation of the ordered array of genetic loci such that the interval between entries has algebraic signs and magnitude proportional to the expected number of crossings over between them and distances are algebraically additive; for example, on a genetic map the combined distance between locus A and locus C is the algebraic sum of the two distances between loci A and B, and B and C.

gene mapping

Determining the location of hereditary information carried on chromosomes. In humans, this requires determining the base pairs (chemical code) of each of the estimated 20,000 to 25,000 genes. Once a gene is mapped, that information may be used to compare abnormal genes with normal ones. Molecular biological techniques may then be used to search for methods of treating and preventing conditions resulting from genetic abnormality.
Synonym: genome mapping; linkage map See: gene splicing
See also: mapping
References in periodicals archive ?
Gene mapping has made it possible to see where the virus hits.
In addition, the knowledge of gene mapping may be used for the design of new therapeutics, including gene therapy, based on DNA sequence information.
It's not hard to imagine the citizens of Pennsylvania or North Dakota shaking their heads at the bill's funding of a barley gene mapping project at Oregon State University or the remodeling of a cafeteria at Crater Lake National Park.
Chugh says, "What we now need is to find out who lives at each address, and what they do for a living." High-density gene mapping and examination of functional pathways and genomic structures are the best ways to identify genetic susceptibilities to lethal arrhythmias.
The researchers, who included gene mapping pioneer Dr Craig Venter, used a male standard poodle as their DNA source.
Experts believe these 'next generation' scientists will be vital to making sense of complex computer data tied to gene mapping and understanding how healthy cells become diseased.
The topics can be put loosely into five categories: gene mapping (including discovery, identification, and localization), expression profiling, protein structure and function, gene therapy, and bioinformatics.
The scientific community has determined that the goal of identifying genes that cause defects will be best advanced through procedures known as gene mapping and gene sequencing.
RECENT developments in the biological sciences, including genomics, the science of gene mapping and manipulation, have the potential to change human life in ways that make the industrial revolution look like a Sunday school picnic.
Hall believes that aggressive investors "who are well versed in such issues as gene mapping" make good candidates for investing in a specialized biotech funds.
"Now we can use either marker-assisted selection to integrate those genes into breeding nucleuses to create less aggressive hogs, or we can clone the genes by using fine gene mapping techniques," Muir says.