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a broad-spectrum antibiotic effective against many gram-positive and gram-negative bacteria; administered orally and intravenously in the treatment of bacterial complication of chronic bronchitis, acute sinusitis, community-acquired pneumonia, gonorrhea, pyelonephritis, and urinary tract infections due to susceptible organisms.
gatifloxacin/gat·i·flox·a·cin/ (gat″ĭ-flok´sah-sin) a fluoroquinoloneantibacterial effective against many gram-positive and gram-negative bacteria.
a broad-spectrum antiinfective.
indications It is used to treat acute bacterial exacerbation of chronic bronchitis, acute sinusitis, community-acquired pneumonia, gonorrhea, and infections caused by susceptible Escherichia coli, Staphylococcus aureus, Haemophilus influenzae, H. parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Neisseria gonorrhoeae, Proteus mirabilis, Chlamydia pneumoniae, Legionella pneumophila, and Mycoplasma pneumoniae.
contraindications Known hypersensitivity to quinolones prohibits its use.
adverse effects Pseudomembranous colitis is a life-threatening effect. Other adverse effects include dizziness, insomnia, paresthesia, tremor, vasodilation, increased aspartate aminotransferase and alanine aminotransferase, pruritus, urticaria, photosensitivity, flushing, fever, and chills. Common side effects include headache, nausea, diarrhea, rash, dyspnea, and pharyngitis.
a fluoroquinolone antibiotic with activity against anaerobic bacteria.