gate


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gate

 [gāt]
1. an electronic circuit that passes a pulse only when a signal (the gate pulse) is present at a second input.
2. a mechanism for opening or closing a protein channel in a cell membrane, regulated by a signal such as increased concentration of a neurotransmitter, change in electrical potential, or physical binding of a ligand molecule to the protein to cause a conformational change in the protein molecule.
3. to open and close selectively and function as a gate.

gate

(gāt),
1. To close an ion channel by electrical (for example, membrane potential) or chemical (for example, neurotransmitter) action.
See also: cardiac gating.
2. Action of a special nerve fiber to block the transmission of impulses through a synapse, for example, gating of pain impulses at synapses in the dorsal horns.
See also: cardiac gating.
3. A device that can be switched electronically to control the passage of a signal.
See also: cardiac gating.
4. To use a physiologic signal, such as an ECG, to trigger an event such as an x-ray exposure or to partition continuously collected data.
See also: cardiac gating.
[O.E. geat]
Cell biology A structure composed of one or more proteins that regulate passage of ions through channels in the cell membrane; gates may be chemically regulated—by neurotransmitters—or voltage regulated—in response to a threshold level of depolarization
Drug slang A regional term for Spanish heroin
Informatics An electronic circuit that performs an operation when the criteria for a logical relation—e.g., AND, or OR—are fulfilled
Immunology verb To limit the size of cells detected and their fluorescence in flow cytometry to increase the purity of cell population being analysed or sorted
Vox populi A new root form derived from the Watergate scandal which toppled the Nixon administration; -gate has been applied to various scandals. Medically-related -gates include AIDSgate and Bloodgate
References in classic literature ?
As Turan had passed through the gateway into the city and taken his unhindered way along the avenue, twenty warriors had entered the city and closed the gate behind them, and then one had taken to the wall and followed along its summit in the rear of Turan, and another had followed him along the avenue, while a third had crossed the street and entered one of the buildings upon the opposite side.
"You were ever a strange man, to whom the gates of distance are no bar.
Not even a single guard was visible before the great entrance gate, nor in the gardens beyond, into which he could see, was there sign of the myriad life that pulses within the precincts of the royal estates of the red jeddaks.
The love of a strong man is ever a lure to a normal woman, and never more strongly did Dede feel the lure than now, looking across the closed gate at Burning Daylight.
They were huddled upon the opposite side of the street at the left of the gate, screaming at the tops of their voices and looking in the direction from which sounds of reinforcements were coming, as though urging on the men and lions that were already too close for the comfort of the fugitives.
Twice more in the darkness the bell at the great gate sounded, and the irruption was repeated, and the grindstone whirled and spluttered.
But Mavra Kuzminichna stood at the closed gate for some time with moist eyes, pensively swaying her head and feeling an unexpected flow of motherly tenderness and pity for the unknown young officer.
Down they charged after them, but the outlaws made good their lead, and soon got through the gate and over the bridge which had been let down by Arthur-a-Bland.
A great peacock strutted proudly across the walk before them, and, as Richard ran, childlike, after it, Lady Maud hastened on to the little postern gate which she quickly unlocked admitting her lover who had been waiting without.
But scarcely had I taken a hundred steps in the direction of the farther gate when the sound of marching troops, the clank of metal, and the squealing of thoats just within the city apprised me of the fact that the Kaolians were already moving toward the other gate.
"Now then," said John to the coachman, "God commands man to do all that is in his power to preserve his life; go, and drive to another gate."
Peter asked her the way to the gate, but she had such a large pea in her mouth that she could not answer.