FABP6

(redirected from gastrotropin)

FABP6

A gene on chromosome 5q23-q35 that encodes the ileal fatty acid-binding protein that stimulates gastric acid and pepsinogen secretion, and which binds bile salts and bilirubins. Isoform 2 is expressed in the lower GI tract and is essential for the survival of colon cancer cells in response to bile acid-induced apoptosis.
References in periodicals archive ?
After uptake into the enterocyte, the transcellular movement of BS is mediated by cytosolic ileal bile acid-binding protein, also known as fatty acid-binding protein 6 or gastrotropin (IBABP, FABP6, gene FABP6), that is cytoplasmically attached to ASBT [30].