gastrointestinal decontamination


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gastrointestinal decontamination

Cleansing of the gastrointestinal tract to remove toxic substances, pills taken in overdose, or microorganisms. Activated charcoal or polyethylene glycol solutions (e.g., GoLYTELY) given orally reduce the uptake of many drugs from the gastrointestinal tract. Before bowel surgery, oral antibiotics (e.g., neomycin) may be given to reduce the number of bacteria within the intestines.
See also: decontamination
References in periodicals archive ?
Gastrointestinal decontamination methods used in a study conducted by Caravati include, vomiting induction using ipecac syrup (58%), activated charcoal alone (9%), gastric lavage combined with activated charcoal (7%), and ipecac syrup combined with activated charcoal (3%) (18).
In summary, the general management of patients who have ingested poisonous or injurious plants should be based on several simple rules, including (1) avoid harm to patients from over-aggressive gastrointestinal decontamination, (2) base initial therapies on presenting toxidromes, and (3) continue therapies with observed positive responses.
Does transportation by ambulance decrease time to gastrointestinal decontamination after overdose?
Although gastrointestinal decontamination using activated charcoal is clearly more convenient, safer, and less expensive than more invasive procedures, there still remain uncertainties about the optimal methods for use and administration with the pediatric population.

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