gastrins


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gas·trins

(gas'trinz),
Hormones secreted in the pyloric-antral mucosa of the mammalian stomach that stimulate secretion of HCl by the parietal cells of the gastric glands; there are three main types: big gastrin (34 aminoacyl residues), little gastrin (17 residues), and minigastrin (14 residues), as well as sulfated derivatives. The C-terminal pentapeptide is also seen in cholecystokinin and cerulein.
[G. gastēr, stomach, + -in]

gas·trins

(gas'trinz)
Hormones secreted in the pyloric-antral mucosa of the mammalian stomach that stimulate secretion of HCl by the parietal cells of the gastric glands; a competitive inhibitor of gastrins is cholecystokinin.
[G. gastēr, stomach, + -in]

gas·trins

(gas'trinz)
Hormones secreted in the pyloric-antral mucosa of the mammalian stomach.
[G. gastēr, stomach, + -in]
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References in periodicals archive ?
Variations in the sulfation of circulating gastrins in gastrointestinal diseases.
Gastrin was the first gastrointestinal hormone to be measured in plasma (1-4).
Today, the picture is changed: Peptic ulcer is caused by Helicobacter pylori infection and does not need gastrin measurement for diagnosis.
Pitfalls in diagnostic Gastrin measurements
The median amidated gastrin concentration in normal serum was 10.5 pmol/L (range, 9.0-18.0 pmol/L), whereas the gastrin-l7-specific ELISA measured significantly lower concentrations (median, 4.0 pmol/L; range, 0.0-8.0 pmol/L; n = 6; P <0.005).
The present examination illustrates that a gastrin-l7specific ELISA measures very low concentrations of gastrin in serum from gastrinoma patients.
Patterns of gastrin components in serum during feeding in normal subjects and duodenal ulcer patients.
Impact of assay epitope specificity in gastrinoma diagnosis
Long term omeprazole therapy in peptic ulcer disease: gastrin, endocrine cell growth and gastritis.
[5] Nonstandard abbreviations: MTC, medullary thyroid carcinoma; MEN, multiple endocrine neoplasia; CT, calcitonin; and GT, gastrin.
Comparison of two provocative tests for calcitonin in medullary thyroid carcinoma: omeprazole vs pentagastrin
1), whereas CCK-B receptors do not discriminate between sulfated and nonsulfated CCK-peptides or between CCK and gastrin peptides (for review, see references 1-3).
The plasma samples were stored at -20 [degrees]C until the measurement of gastrin and CCK.
Accurate measurement of cholecystokinin in plasma
Gastrin is a linear peptide hormone produced by gastrin cells, having regulatory functions of acute gastric acid secretion as well as the gastric epithelial cell population (Kovac et al.
TA had an effect on the [H.sup.+]/[K.sup.+]-ATPase, the secretion of acid and gastrin level, but had little effect on the mucosal repair and the activity of pepsin in a PL induced ulcer.
Alkaloids from Mahonia bealei posses anti-[H.sup.+]/[K.sup.+]-ATPase and anti-gastrin effects on pyloric ligation-induced gastric ulcer in rats

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