The upper and lower gastric pit epithelium was purple and red, respectively.
As we know from Table I that the reactions to PAS were positive in the mucosal epithelial and gastric pit in the fundic glandular area, and more strongly positive in the gastric pit.
Observed in (a): disorganization of the gastric glands (arrows) and of the columnar simple epithelium in the gastric pits
(enlarged detail, arrowhead) with cellular necrosis (dashed arrow); in (b): columnar simple epithelium of the pits (enlarged detail) and well-preserved gastric glands (arrows); in (c): gastric mucosa with slight exfoliations of the columnar simple epithelium and unpreserved gastric mucosa (asterisk); in (d): preserved gastric mucosa (asterisk) with exfoliations of discrete columnar epithelium (enlarged detail, arrow); and in (e): preserved gastric mucosa (asterisk) and simple columnar simple epithelium (enlarged detail).
SM, submucous layer; LM, longitudinal muscle; CM, circular muscle; LMM, lamina muscularis muscosae; GP, gastric pits
The fundic glands are simple, branched tubular glands that extend from the bottom of the gastric pits
to the muscularis mucosae (Figure 1), and are formed by four functional types of cells: mucous neck cells, chief cells, enteroendocrine cells, parietal cells (also called oxyntic cells), and undifferentiated cells.
The magnified views of Hp-related gastritis significantly differed from normal mucosa presenting collecting venules and true capillaries forming a network with gastric pits
in the center .
The stomach of the pangolin and rat are characterized with numerous gastric pits
with the zymogenic cells located towards the base of the gland, the parietal cells along the length and the mucus-secreting cell at the luminal surface (Fig 1a & b).