gastric mucin

gas·tric mu·cin

a white or yellowish powder that forms a viscous opalescent fluid with water, prepared from mucosa of hog's stomach by pepsin-hydrochloric acid digestion and precipitation of the supernatant fluid with 60% alcohol; used in peptic ulcer for its protective and lubricating action.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 11p15.5 that encodes a gel-forming glycoprotein of gastric and respiratory tract epithelia, which protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles, which are subsequently removed by the mucocilary system.

Molecular pathology
MUC5A stains are positive in foveolar dysplasia.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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References in periodicals archive ?
Clinicopathological characteristics of duodenal epithelial neoplasms: focus on tumors with a gastric mucin phenotype (pyloric gland-type tumors).
The gastric mucus secretion, the content of gastric mucin and their precursor hexosamine, is reduced.
Munich, (QNA) - A team from the Technical University of Munich (TUM) has now succeeded in demonstrating that contact lenses coated with purified porcine gastric mucin do not cause damage to the eye anymore.
[20] Mucus release promotes epithelial recovery by neutralizing luminal acid, protecting against pepsin, oxidants, and other damaging agents [22] with hexosamine as the main constituent of gastric mucin. [23]
Conclusion: Permanent impairment in the conjugation of cell and tissue components in mucosa accompanied by the change of an epithelial layer synthetic function with the impaired physicochemical properties of gastric mucin results in intestinal metaplasia as early as in childhood.
(black mulberries) and Rubus niveus Thunb (raspberries), assessing their antioxidant properties and effects on gastric mucin content, as well as on [H.sup.+]/[K.sup.+]-ATPase activity.
Effect of acetylsalicylic acid on gastric mucin viscosity, permeability to hydrogen ion, and susceptibility to pepsin.
Likewise, HGF aids angiogenesis, through multiple mechanisms including COX activation, and increases EGF expression that eventually accelerates gastroduodenal ulcer healing by increasing gastric mucin and diminishing gastric acid secretion [38].
We demonstrated the molecular mechanisms of its antiulcerogenic action: enhanced cytoprotection accomplished by induction of gastric mucin secretion and [PGE.sub.2] biosynthesis and antioxidant and antiinflammatory properties.
Slomiany, "Platelet activating factor mediates helicobacter pylori lipopolysaccharide interference with gastric mucin synthesis," IUBMB Life, vol.
In a study by Araya (12) and Neira, (26) the metacyclic trypomastigotes using gp82 present in its membrane were shown to promote adherence to gastric mucin. Thus, host-parasite interaction is mediated by gp82 in cells that trigger signals that induce calcium release, an event essential for the internalization of T.