gastric mucin

gas·tric mu·cin

a white or yellowish powder that forms a viscous opalescent fluid with water, prepared from mucosa of hog's stomach by pepsin-hydrochloric acid digestion and precipitation of the supernatant fluid with 60% alcohol; used in peptic ulcer for its protective and lubricating action.

gastric mucin

Etymology: Gk, gaster, stomach; L, mucus
a viscous secretion of glycoproteins produced from the mucous membrane lining of swine stomachs and formerly used in the treatment of peptic ulcers.


A gene on chromosome 11p15.5 that encodes a gel-forming glycoprotein of gastric and respiratory tract epithelia, which protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles, which are subsequently removed by the mucocilary system.

Molecular pathology
MUC5A stains are positive in foveolar dysplasia.
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References in periodicals archive ?
20] Mucus release promotes epithelial recovery by neutralizing luminal acid, protecting against pepsin, oxidants, and other damaging agents [22] with hexosamine as the main constituent of gastric mucin.
51) In the era of conversion to HPV testing as the primary screening modality it has been proposed that molecular testing for gastric mucin should be added to HPV testing in order to provide coverage for gastric ADC.
Munich, (QNA) - A team from the Technical University of Munich (TUM) has now succeeded in demonstrating that contact lenses coated with purified porcine gastric mucin do not cause damage to the eye anymore.
Conclusion: Permanent impairment in the conjugation of cell and tissue components in mucosa accompanied by the change of an epithelial layer synthetic function with the impaired physicochemical properties of gastric mucin results in intestinal metaplasia as early as in childhood.
Effect of acetylsalicylic acid on gastric mucin viscosity, permeability to hydrogen ion, and susceptibility to pepsin.
In a study by Araya (12) and Neira, (26) the metacyclic trypomastigotes using gp82 present in its membrane were shown to promote adherence to gastric mucin.
Alterations in gastric mucin with malignant transformation: novel pathway for mucin biosynthesis.
The organisms are generally located near the mucosal surface in the gastric mucin (Figure, B), rather than in the gastric pits, and are not invasive.
MUC5AC, on the other hand, is a gastric mucin type and as such it is not anticipated in the colon.
In comparison with gastric foveolar-type adenomas, PGAs do not have a well-formed mucin cap; the presence of the neutral gastric mucin cap can be examined by a periodic acid-Schiff/Alcian blue stain.