The incidence of primary GI-NHL is reported to be higher in Eastern countries than in Western countries, and high-grade histopathological types of gastric lymphoma
are more common in Turkey and Middle Eastern countries than in Western countries [4, 5].
pylori-infected chronic gastritis develop peptic ulcerations, distal gastric adenocarcinoma, or gastric lymphoma
Higher NHL rates in males are seen across all subtypes, from more common intranodal subtypes such as diffuse large B-cell lymphoma (Hedstrom et al., 2015), follicular lymphoma (Nabhan et al., 2016), and mantle cell lymphoma (Aschebrook-Kilfoy, Caces, Ollberding, Smith, & Chiu, 2013), to the rarest forms of extranodal NHL such as primary central nervous system lymphoma (Villano, Koshy, Shaikh, Dolecek, & McCarthy, 2011) and primary gastric lymphoma
(Padhi et al., 2012).
Primary Gastric Lymphoma
with Spontaneous Perforation: Report of a Case.
pylori in the gastric mucosa is associated with chronic active gastritis, which may lead to the development of peptic ulcer, gastric carcinoma and even gastric lymphoma
Regression of primary low-grade B-cell gastric lymphoma
of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori.
Pylori is known to have a relationship with chronic active gastritis, peptic ulcer, primary low-grade (B-cell) gastric lymphoma
(mucosa-associated lymphoid tissue lymphoma), and gastric adenocarcinoma (8).
CLE criteria for gastric lymphoma
were based on recent established findings as follows [10-12]: (1) darkened areas made up of small roundish cells of similar size and morphology for the mucosa-associated lymphoid tissue (MALT) lymphoma or larger roundish cells for diffuse large B-cell lymphoma (DLBCL); abnormal cells in a dense arrangement; (2) cellular infiltrates typically affecting but not limited to the lamina propria; (3) cellular invasion of various epithelial structures; (4) altered tissue morphology to complete loss of structural integrity of the epithelium.
Berdel et al., "Treatment results in localized primary gastric lymphoma
: data of patients registered within the German Multicenter Study (GIT NHL 02/96)," Journal of clinical oncology, vol.
pylori when it is present in patients with documented gastric or duodenal ulcers or gastric lymphoma
Classification of GC into intestinal and diffuse type was made according to Lauren's criteria.6 All cases of malignant lymphoma were primary gastric lymphoma
, as the patients did not have disseminated disease at the time of presentation, and no generalised lymphadenopathy.
Rodriguez et al., "Helicobacter pylori infection and gastric lymphoma
," The New England Journal of Medicine, vol.