gap junctions


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gap junctions

aligned protein membrane channels of two adjacent cells, allowing passage of low-molecular-weight solutes (ions, chemical messengers, amino acids and glucose) directly between cells

gap junctions

regions of high and special ionic permeability between closely apposed cells. They are places at which cells exchange molecules of large size and provide an avenue by which developing cells can influence each other. Called also nexus.

neuronal gap junctions
very tight contacts between some neurons permitting the almost instant transmission of impulses from one neuron to the other; structural elements extend across the gap conferring a continuity of cytoplasm between the cells.
References in periodicals archive ?
2009) The diverse functional roles and regulation of neuronal gap junctions in the retina.
For these reasons, all anti-apoptotic treatment modalities such as a Ca-sensitiserinotropic agent levosimendan, caspase and/or Poly (ADP-ribose) polymerase (PARP) inhibition, inhibition of Bax using antisense technology, adenine nucleotide transporter (ANT) antibodies, gap junction and microtubule inhibitors in the treatment of myocardial ischaemia/ reperfusion injury can individually exert beneficial therapeutic effects.
11) Additionally, in rabbit, the communication through gap junctions early in IL-1P signal transduction is critical to the process of cytokine-regulated secretion of metalloproteinases by synovial cells.
Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle," Circulation, vol.
At the cumulus cells, MAPK activity is likely to trigger the expression of Meiosis Activating Sterol [MAS] from cumulus to oocyte through gap junctions and will induce MPF.
Gap junction formation in myometrium; Control by estrogens progesterone and prostaglandins.
Notwithstanding the undisputed importance of the synaptic connections and their assisted delivery of messages from the splanhnic nerve to the adrenal chromaffine cells, the gap junction mediating communication serves as an ideal structure to promote intercellular connections in the adrenal medulla.
That was the main finding: We do get very good electrical coupling, which we call functional gap junction connections.
Gap junctions in the brain; physiological and pathological roles.
13 Gap junctions are particularly important to your skin because it is highly dependent upon intercellular communication for vital metabolic processes related to growth and reproduction.
In ovaries, connexin 43 (Cx43), encoded by Gja1, has been found to be the main connexin expressed in developing follicles forming the gap junctions coupling granulosa cells (20-23).