glutathione

(redirected from gamma-Glutamyl-cysteinyl-glycine)
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glutathione

 [gloo″tah-thi´ōn]
a tripeptide of glutamic acid, cysteine, and glycine; the reduced form (GSH) serves as a reducing agent in many biochemical reactions, being converted to oxidized glutathione (GSSG) in which the cysteine residues of two glutathione molecules are connected by a disulfide bridge. Reduced glutathione is important in protecting erythrocytes from oxidation and hemolysis; deficiency causes sensitivity to oxidant drugs.

glu·ta·thi·one (GSH),

(glū'tă-thī'ōn),
A tripeptide of glycine, l-cysteine, and l-glutamate, with l-glutamate having an isopeptide bond with the amino moiety of l-cysteine. Glutathione has a wide variety of roles in a cell; it is the most prevalent non-protein thiol. Glutathione disulfide (GSSG) consists of two glutathiones linked through a disulfide bridge; the term oxidized glutathione for GSSG should be avoided because it includes the sulfones and sulfoxides. (The term reduced glutathione is not necessary because glutathione is the thiol form.) A deficiency of glutathione can cause hemolysis with oxidative stress. It is also used in the course of intermediary metabolism as a donor of thiol (SH) groups and is essential for detoxification of acetaminophen.
See also: oxidized glutathione, reduced glutathione, glutathione reductase.

glutathione

(glo͞o′tə-thī′ōn′)
n.
A tripeptide, C10H17N3O6S, of glycine, cysteine, and glutamic acid that occurs widely in plant and animal tissues and is important in biological oxidation-reduction reactions.

glutathione

A ubiquitous tripeptide with antioxidant activity involved in CNS metabolism, serving as a coenzyme for some enzymes of oxidation-reduction systems, transmembrane amino acid transport, maintenance of red cell integrity and prevention of H2O2 accumulation in red cells.
 
Glutathione-rich foods
Asparagus, avocado, broccoli, oranges, squash, strawberries and watermelon.

glutathione

γ-Glutamyl-cysteinyl-glycine A ubiquitous antioxidant tripeptide involved in CNS metabolism, which serves as a coenzyme for some enzymes of oxidation-reduction systems, transmembrane amino acid transport, maintaining RBC integrity, and prevention of H2O2 accumulation in RBCs. See Antioxidant, Antioxidant therapy, Free radical, Free radical scavenger.

glu·ta·thi·one

(GSH) (glū'tă-thī'ōn)
1. The principal low molecular weight thiol compound of living plant cells; used in the course of intermediary metabolism as a donor of thiol (SH) groups; essential for detoxification of acetaminophen.
2. Compound has a wide variety of roles in a cell. A deficiency can cause hemolysis with oxidative stress.

glutathione

A tripeptide amino acid derivative that protects red cells from oxidative damage and, in the form of the enzyme glutathione peroxidase, plays an important role in detoxifying hydrogen peroxide and organic peroxides produced in the body. Glutathione also participates in the transport of amino acids from one cell to another.

Glutathione

A molecule that acts as a co-enzyme in cellular oxidation-reduction reactions.

glu·ta·thi·one

(glū'tă-thī'ōn)
A tripeptide of glycine, l-cysteine, and l-glutamate; essential for detoxification of acetaminophen.
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