LGALS1

(redirected from galectin-1)

LGALS1

A gene on chromosome 22q13.1 that encodes a galectin family-type carbohydrate-binding protein, which is implicated in modulating cell-cell and cell-matrix interactions, and may regulate apoptosis, cell proliferation and cell differentiation.
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Thermodynamic binding studies of bivalent oligosaccharides to galectin-1, galectin-3, and the carbohydrate recognition domain of galectin-3.
Intra-articular lentivirus-mediated delivery of galectin-3 shRNA and galectin-1 gene ameliorates collagen-induced arthritis.
Galectin-1 and galectin-3 binding pattern expression in renal cell carcinomas.
Galectin-1 is released during adipocyte differentiation and is associated with fat which is one of the important factors for meat quality.
Two remaining papers address special topics: targeting galectin-1 with self-assembled multivalent pseudopolyrotaxanes and de novo synthesis of biofunctional carbohydrate-encapsulated quantum dots.
Dex produced a dose-dependent increase in galectin-1 synthesis and release into the medium with confluent cultures in serum-free medium, but had no effect with serum present.
Studies Demonstrate DAVANAT([R] )Binds To Galectin-1 and Galectin-3 Receptors That Control Angiogenesis and the Tumor's Ability To Evade the Immune System
Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer.
Differential expression of galectin-1 and galectin-3 in thyroid tumors.
Peer reviewed studies have demonstrated that Galectin-1 and Galectin-3 induce apoptosis (cell death) in immune system T cells ("Galectins," Chapter 7, Wiley, 2008).
Nuclear and Cytoplasmic Localization of Galectin-1 and Galectin-3 and their Roles in pre-mRNA Splicing (John L.