galanin


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galanin

(găl′ăn-ĭn)
A peptide neurotransmitter with numerous functions in the central nervous system and the gastrointestinal tract. It stimulates gastrointestinal smooth muscle contraction and inhibits insulin secretion.
References in periodicals archive ?
Another neuropeptide is galanin, a 29-amino acid peptide that was discovered in 1983 in the porcine intestine as an orexigenic neuropeptide; it is mainly synthesized in the central and peripheral nervous systems and gastrointestinal tract.
Topiramate normalizes hippocampal NPY-LI in flinders sensitive line "depressed" rats and upregulates NPY, galanin, and CRH-LI in the hypothalamus: Implications for mood-stabilizing and weight loss-inducing effects.
A similar kind of institutional critique was tackled in part by an installation by Nick Galanin (Tlingit/Aleut, 1979).
Vasoactive intestinal peptide, oxytocin, galanin, and PHM-27 induce prolactin release, as does serotonin, which is thought to be the major stimulating factor accounting for the rise of prolactin during REM sleep.
Son et al., "Coevolution of the spexin/galanin/kisspeptin family: spexin activates galanin receptor type II and III," Endocrinology, vol.
Berggren, "Suppression of insulin release by galanin and somatostatin is mediated by a G-protein.
Extrinsic control of the release of galanin and VIP from intrinsic nerves of isolated, perfused, porcine ileum.
"There is some suggestion that a neuropeptide called Galanin might be responsible as animal studies have linked it to cravings for both fatty foods and alcohol.
One-year walking intervention, with 3, 40-min sessions*[wk.sup.-1] produced changes in white matter in the frontal and temporal regions that improved short-term memory (57), increased the levels of growth factors, including brain-derived neurotrophic factor (BDNF) as well as insulin-like growth factor type 1 (IGF-1), and vascular endothelial growth factor (VEGF) (57), promote neuroplasticity and facilitate learning and memory through the release of neurotrophins, glia-derived neurotrophin (GDNF), nerve growth factor (NGF), and galanin (22).