Galactose-alpha-1,3-galactose | definition of galactose-alpha-1,3-galactose by Medical dictionary
A carbohydrate found in many nonhuman mammalian tissues. It can stimulate delayed immune responses, esp. food allergies, in sensitized people who eat meat. Synonym: alpha-gal
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References in periodicals archive
The presence of the epitope galactose-alpha-1,3-galactose
([alpha]Gal) synthesized by alpha-1,3-galactosyltransferase ([alpha]GT) on the surface of porcine cells induces HAR [4,5].
The findings were published by the scientific journal Nature Biotechnology as a correspondence entitled Chinese Hamster Ovary Cells Can Produce Galactose-alpha-1,3-Galactose
Antigens on Proteins.
The unique part on this monoclonal antibody drug responsible for these cross-reactions was determined to be the carbohydrate structure galactose-alpha-1,3-galactose
; found on both the monoclonal antibody protein and beef proteins.