fusin


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Related to fusin: nuclear fusion, VMware Fusion

fu·sin

(fyū'zin),
A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell.
[fuse, fr. L. fundo, pp. fusum, to melt, + -in]

CXCR4

A gene on chromosome 2q21 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which binds specifically to stromal cell-derived factor-1, transducing a signal by increasing intracellular calcium ions and enhancing MAPK1/MAPK3 activation. It acts as a receptor for extracellular ubiquitin, is involved in haematopoiesis and in cardiac ventricular septum formation, plays a role in gastrointestinal tract vascularisation by regulating vascular branching and/or remodelling in endothelial cells, may be involved in cerebellar development and, in the CNS, may mediate hippocampal-neuron survival.

Molecular pathology
CXCR4 acts with the CD4 to support HIV entry into cells; it is highly expressed in breast cancer cells. CXCR4 mutations cause WHIM (warts, hypogammaglobulinaemia, infections, and myelokathexis) syndrome.

fu·sin

(fyū'zin)
A G protein-linked receptor present on certain human cells that is thought to be required for HIV fusion with a target cell.
[fuse, fr. L. fundo, pp. fusum, to melt, + -in]
References in periodicals archive ?
Tiradito reinterprets kinilaw using raw tuna loin covered with a gel made of coconut milk, calamansi and tabon-tabon, a souring ingredient, which was introduced at Madrid Fusin last year by Segismundo and Fores.
Like last year, the room at Madrid Fusin was filled with Filipino pride perhaps because we saw ourselves in Gonzalez who personifies the Philippine and Spanish connection, a man who appreciates himself the more he learns about his roots.
(26) For what reason did the Cynics criticise traditional piety: because they rejected the existence of the gods, because they considered religion to be a useless activity detracting from ethical progress, or perhaps because they regarded traditional polytheism as obstructing the way of an Antisthenic theology of a single God kata fusin?
It may be concluded that, even though the early Cynics refrained from making epistemological claims about God/the gods, some form of theistic conception is not incompatible with their thinking, the most likely being that of the 'one god kata fusin' as expressed by Antisthenes.
Fusin binds to a molecule called stromal-cell-derived factor 1, or SDF-1, two research groups now report.
Like fusin, CC-CKR-5 is a receptor, a protein that normally binds to extracellular molecules and transmits signals into the cell.
Other researchers hail the long-awaited identification of this protein, which Berger's group calls fusin, as a major advance in scientists' knowledge of HIV's life cycle.