fusidic acid


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fu·sid·ic ac·id

(fyū-sid'ik as'id),
A fermentation product of Fusidium coccineum, a parasitic fungus on the plant Veronica; inhibits protein synthesis and the accumulation of ppGpp.
Synonym(s): ramycin

fusidic acid

A steroid antibiotic used in the form of sodium fusidate against penicillin-resistant (beta-lactamase-producing) staphylococci. It has no value against streptococci and is usually given in conjunction with another antibiotic such as FLUCLOXACILLIN. Brand names are Fucidin and Fucithalmic.

fusidic acid

A product used as an antibiotic agent in solution 1%. It is synthesized as sodium fusidate from the microorganism Fusidium coccineum. It is effective against gram-positive bacteria. It is used in the treatment of bacterial blepharoconjunctivitis, especially staphylococcal infection.
References in periodicals archive ?
Most of the multidrug resistant isolates were sensitive to Polymyxins B, Tazocin and Fusidic acid (Fig.
aureus resistance rates to fusidic acid, widely used outside of the United States, vary greatly among studies and demonstrate the importance of knowing local resistance patterns.
As recommended by the EUCAST, fusidic acid MIC values of [less than or equal to] 1 [micro]g/mL and > 1 [micro]g/mL were set as signifying susceptible and resistant types, respectively.
has completed the acquisition of fusidic acid from Melinta Therapeutics, the company said.
Novel therapeutics company Arrevus Inc revealed on Tuesday the completion of the acquisition of fusidic acid from Melinta Therapeutics for undisclosed fee.
The following genes conferring resistance to the respective antibiotics were screened: blaZ (penicillin), mupA, ileS (mupirocin), aac(6')-aph(2") (gentamicin), ermA, ermB, ermC, msrA (erythromycin), vanA, vanB (vancomycin), cfr (linezolid), tetA, tetB (tetracycline), and fusB, fusC, fusD (fusidic acid).
In our study, it was observed that in 55 (36.9%) of patients topical steroid preparations were used as monotherapy whereas in 94 (63%) of patients topical steroids were combined with salicylic acid, gentamycin, clotrimazole, and fusidic acid as shown in Table 5.
A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma.
The report of CST of the urine sample after 48 hours of aerobic incubation revealed the causative organism to be Proteus spp giving sensitivity (+++) to Amoxyclav, Amoxycillin/ Sulbactam, Ampicillin/Sulbactam, Ampicillin/ Cloxacillin, Amikacin, Cefoxitin, Ceftrioxone/ Sulbactam, Cefuroxime, Co-Trimoxazole, Ceftazidime/ Calvulanic acid, Cefoperazone, Cefoperazone/ Sulbactam, Cephalexin, Imipenem, Fusidic Acid, Gentamicin, Linezolid, Novobiocin, Moxifloxacin, Enrofloxacin, Ofloxacin, Norfloxacin, Ciprofloxacin, Nitrofurantoin, Oxytetracycline, Pipracillin/ Tazobactam, Netilin, Meropenem, Rifampicin, Cefpodoxime, Tobramycin and Vancomycin.
This might be explained by considering that, in previous studies [33], fusidic acid (0.3-300 [micro]M) was shown to stimulate the MRP2 transporter (canalicular efflux) in vitro, as indicated by the increased efflux of LTC4 (leucotriene C4) using MRP2 transfected membrane vesicles.