As the infection progresses into furious rabies
symptoms may appear such as insomnia, agitation, anxiety, aggressiveness, muscle spasms, restlessness, confusion, hallucinations, abnormal thoughts, excess salivation, difficulty in swallowing, and fear of water.
is the classic "mad dog" form, while dumb rabies paralyses the victim's jaw.
Paralytic rabies is characterized by flaccid paralysis in the bitten limb, which ascends symmetrically or asymmetrically, whereas the furious rabies
manifests hyper-excitability, autonomic dysfunction, hydrophobia, and aerophobia (13,14).
The clinical picture includes a prodromal stage followed by severe neurological manifestations in the form of undue salivation, aerophobia and hydrophobia (furious rabies
) or paralysis (dumb rabies).
Two-thirds of human patients infected with dog RABV variants show clinical signs of classic furious rabies
, the remaining third develop paralytic rabies.
There are two types: furious rabies
, which accounts for four out of five cases, involves the victim exhibiting aggressive behavior such as thrashing out or biting, excessive production of saliva and hallucinations; and dumb or paralytic rabies, which involves the victim losing sensation, hydrophobia (fear of water) and muscles spasm.
The patient develops hyperactivity, called furious rabies
, or paralysis, called dumb rabies.
Typical furious rabies
occurs as an encephalitis, often with characteristic features such as hydrophobia and salivation, following a brief, nonspecific, febrile prodrome.
An animal with furious rabies
is "hostile, may bite at objects, and have an increase in saliva.
Deaths from symptomatically identifiable furious rabies
in India: A nationally representative mortality survey.
A total of 779 children had no clinical features of furious rabies
at the time of admission; 487 of these children had malaria parasitemia, including 341 with a BCS [less than or equal] 2/5 who met the case definition of cerebral malaria.