furanocoumarin

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furanocoumarin

(fyūr-a-nō-kū-mah'rinz),

Member of a group of chemical compounds found in grapefruit, which includes bergamottin and 6'7'-dihydroxybergamottin. Inhibit CYP450 3A4, particularly in the GI tract.
See also: bergamottin.

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bergamottin

References in periodicals archive ?

There are many phytochemical studies on Heracleum species that mainly focused on furanocoumarins (8,9) and furanocoumarin glycosides, (10,11) together with alkaloids, (12) polyacetylenes, (13) and flavonoids.

Flavonoid Glycosides from Heracleum pastinaca Fenzl/Heracleum pastinaca Fenzl'in Flavonoit Glikozitleri

In third phase, docking studies were extended to furanocoumarin derivatives.

Inhibitory Mechanism Exhibited by Phenol-based Natural Products against DNA Polymerase [alpha] from Psoralea corylifolia by Molecular Docking

Non-volatiles (PMF, furanocoumarin) make up the remaining amount of the essential oil.

Exploring the Complexities and Caveats of Safe Internal Use of Essential Oils for Pain: Highlighting Intestinal Discomfort, Part 1

Hu, "A new dimeric furanocoumarin from Notopterygium incisum," Chinese Chemical Letters, vol.

Simultaneous Determination of Bergapten, Imperatorin, Notopterol, and Isoimperatorin in Rat Plasma by High Performance Liquid Chromatography with Fluorescence Detection and Its Application to Pharmacokinetic and Excretion Study after Oral Administration of Notopterygium incisum Extract. (Research Article)

Zangerl, "Adaptive significance of furanocoumarin diversity in Pastinaca sativa (Apiaceae)," Journal of Chemical Ecology, vol.

Differential Effects of Angelicin Analogues on NF-[kappa]B Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells

Honda et al., "Chemical constituents of Prangos tschimganica; structure elucidation and Butylisocoumarins absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity," Chemical & Pharmaceutical Bulletin, vol.

Changes of Metabolomic Profile in Helianthus annuus under Exposure to Chromium(VI) Studied by capHPLC-ESI-QTOF-MS and MS/MS

The data was organized as a tensor of dimensions: four genes (MDR1, MRP, LRP, and BCRP2), five cell lines (HL-60, HL-60/X1, HL-60/MX2, CEM/C1, and CCRF/ CEM), and 8 furanocoumarin derivatives: isopimpinellin (ISO), bergapten (BER), xanthotoxol (XOL), xanthotoxin (XIN), byakangelicin (BIN), byakangelicol (BOL), heraclenin (HEC), phellopterin (FEL), and 12 simple coumarins derivatives: herniarine (HER), aesculetin (AET), dihydrocoumarin (DHD), coumarin (COU), aesculin (AEL), umbelliferone (UMB), 4-methylo-7-methoxycoumarin (4,7M), 4-methylo7-ethoxycoumarin (4,7E), 7-methylocoumarin (7ME), 6methylocoumarin (6ME), 0,0-dimethylofraxetin (OOD), and scoparone (SCO).

Modulation of Multidrug Resistance Gene Expression by Coumarin Derivatives in Human Leukemic Cells

Effect of maturity, processing, and storage on the furanocoumarin composition of grapefruit and grapefruit juice.

Grapefruit juice and psychotropics: how to avoid potential interactions

[37] Vimal V, Devaki T Linear furanocoumarin protects rat myocardium against lipidperoxidation and membrane damage during experimental myocardial injury.

Metabolitos secundarios de Chaptalia meridensis

Leaves and stalks of celery contain phenols, furanocoumarin, psoralen, bergapten, fully and xanthotoxin that their amount is changing from 12 to 50 mg/kg [13].

The effects of hydro-alcoholic extract of celery on lipid profile of rats fed a high fat diet

The linear furanocoumarin imperatorin and the coumarin osthole extracted from Cnidium monnieri (L.) Cusson fruit were effective against larvae of Culex pipiens pallens Coquillett and Ae.

Evaluation of halogenated coumarins for antimosquito properties

(24.) Guo LQ, Fukuda K, Ohta T, Yamazoe Y: Role of furanocoumarin derivatives on grapefruit j uice-mediated inhibition of human CYP3A activity.