Effect of maturity, processing, and storage on the furanocoumarin
composition of grapefruit and grapefruit juice.
37] Vimal V, Devaki T Linear furanocoumarin
protects rat myocardium against lipidperoxidation and membrane damage during experimental myocardial injury.
Leaves and stalks of celery contain phenols, furanocoumarin
, psoralen, bergapten, fully and xanthotoxin that their amount is changing from 12 to 50 mg/kg .
Guo LQ, Fukuda K, Ohta T, Yamazoe Y: Role of furanocoumarin
derivatives on grapefruit j uice-mediated inhibition of human CYP3A activity.
In vitro metabolism of a linear furanocoumarin
(8-methoxypsoralen, xantho-toxin) by mixed-function oxidases of larvae of black swallowtail butterfly and fall arrnyworm.
PAL is also known to be involved in the lignification process and as a key enzyme in phenylpropanoid biosynthetic pathway, which is the gateway to many plant secondary metabolites such as flavonoids pigments, furanocoumarin
, isoflavonoid, phytoalexin, wound protectant hydroxycinnamic acid esters and aromatic compound in the plant defense system (Dixon et al.
Grapefruit contains the flavonoids, naringenin and furanocoumarin
bergamottin--inhibitors of intestinal CYP3A4.
AFG2), are furanocoumarin
derivatives and potent liver carcinogens for
Since then, several natural compounds in grapefruit have been identified that are involved in the food-drug interaction, including the flavonoid naringin and the psoralen furanocoumarin
Role of furanocoumarin
derivatives on grapefruit-mediated inhibition of human CYP3A4 activity.
induction in wild parsnip; Zangerl and Berenbaum 1995), others have been reported to occur range of spatial scales, from WP to single-leaf responses (e.
Thus, an evolutionary increase in production of any specific furanocoumarin
would be constrained by selection for increased production of others.