furanocoumarin


Also found in: Wikipedia.

furanocoumarin

(fyūr-a-nō-kū-mah'rinz),
Member of a group of chemical compounds found in grapefruit, which includes bergamottin and 6'7'-dihydroxybergamottin. Inhibit CYP450 3A4, particularly in the GI tract.
See also: bergamottin.
Mentioned in ?
References in periodicals archive ?
There are many phytochemical studies on Heracleum species that mainly focused on furanocoumarins (8,9) and furanocoumarin glycosides, (10,11) together with alkaloids, (12) polyacetylenes, (13) and flavonoids.
Zangerl, "Adaptive significance of furanocoumarin diversity in Pastinaca sativa (Apiaceae)," Journal of Chemical Ecology, vol.
Honda et al., "Chemical constituents of Prangos tschimganica; structure elucidation and Butylisocoumarins absolute configuration of coumarin and furanocoumarin derivatives with anti-HIV activity," Chemical & Pharmaceutical Bulletin, vol.
The data was organized as a tensor of dimensions: four genes (MDR1, MRP, LRP, and BCRP2), five cell lines (HL-60, HL-60/X1, HL-60/MX2, CEM/C1, and CCRF/ CEM), and 8 furanocoumarin derivatives: isopimpinellin (ISO), bergapten (BER), xanthotoxol (XOL), xanthotoxin (XIN), byakangelicin (BIN), byakangelicol (BOL), heraclenin (HEC), phellopterin (FEL), and 12 simple coumarins derivatives: herniarine (HER), aesculetin (AET), dihydrocoumarin (DHD), coumarin (COU), aesculin (AEL), umbelliferone (UMB), 4-methylo-7-methoxycoumarin (4,7M), 4-methylo7-ethoxycoumarin (4,7E), 7-methylocoumarin (7ME), 6methylocoumarin (6ME), 0,0-dimethylofraxetin (OOD), and scoparone (SCO).
Effect of maturity, processing, and storage on the furanocoumarin composition of grapefruit and grapefruit juice.
[37] Vimal V, Devaki T Linear furanocoumarin protects rat myocardium against lipidperoxidation and membrane damage during experimental myocardial injury.
Leaves and stalks of celery contain phenols, furanocoumarin, psoralen, bergapten, fully and xanthotoxin that their amount is changing from 12 to 50 mg/kg [13].
The linear furanocoumarin imperatorin and the coumarin osthole extracted from Cnidium monnieri (L.) Cusson fruit were effective against larvae of Culex pipiens pallens Coquillett and Ae.
(24.) Guo LQ, Fukuda K, Ohta T, Yamazoe Y: Role of furanocoumarin derivatives on grapefruit j uice-mediated inhibition of human CYP3A activity.