Following on from her article on Acanthamoeba keratitis (OT, September 19, 2014), Nicole Carnt turns her attention to fungal
Though these features suggested a fungal
hyphae were not demonstrable.
Some of the children who didn't meet the criteria for SAFS diagnosis had high IgE levels but no evidence of fungal
sensitization, or evidence of fungal
sensitivity but normal IgE levels.
In general, management of allergic fungal
sinusitis requires a combination of surgery and medical therapy to achieve the best long-term clinical outcome.
endophytes slip into plant leaves and stems to set up housekeeping between, or even inside, plant cells.
Routine monitoring of fungal
contamination is most effective using the pour-plate or Petri film method and incubating the samples for 5 days, said Anderson.
In all patients with sinusitis, the extent of disease should be assessed with physical examination and computed tomography to look for evidence of calcification within the sinuses, which is highly suggestive of fungal
If water is released into a typical building environment, fungal
growth can begin within 12 hours, and colonization can occur within two to three days.
GPC Biotech's lead anti-fungal
drug discovery program is a novel approach directed towards GGTase type 1 which regulates an important signaling pathway required for fungal
cell wall integrity.
The company also markets Amphotec(R), an FDA-approved lipid-complexed form of amphotericin B for the treatment of invasive aspergillosis, a life-threatening fungal
Prophylactic administration of fluconazole after liver transplantation reduces the rate of fungal
infection, a fairly common consequence of posttransplant immunosuppressive therapy.
Anderson, a fungal
specialist at the University of Toronto.