fundus albipunctatus

fun·dus al·bi·punc·ta·'tus

[MIM*136880]
a nonprogressive disorder of the retinal pigment epithelium characterized by numerous discrete, white dots; night blindness is a feature; autosomal dominant and recessive forms have been suggested.
Farlex Partner Medical Dictionary © Farlex 2012

fundus albipunctatus

A form of fleck retina disease (OMIM:136880) characterised by discrete, uniform white dots over the entire ocular fundus, with greatest density in the midperiphery and no macular involvement. Is generally accompanied by night blindness; autosomal recessive and autosomal dominant forms have been described.

Molecular pathology
Fundus albipunctatus has been linked to a mutations of RDH5 on chromosome 12q13.2 and RLBP1 on chromosome 15q26.1.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

fundus albipunctatus

An autosomal recessive form of night blindness in which the retina is flecked or pigmented, and resynthesis of rhodopsin is delayed.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Fundus Albipunctatus. We included 3 unrelated patients (aged 20, 35, and 8 years) with fundus albipunctatus.
Fundus albipunctatus is considered to be a form of congenital stationary night blindness because of the predominant stationary nature of the disease and associated night blindness.
The presumed accumulation of cis-retinol and cis-retinyl esters in the RPE because of 11-cis-retinol dehydrogenase deficiency is responsible for the formation of white flecks in RDH5 mutation-associated fundus albipunctatus [36, 37] (Figure 7).
Lorenz et al., "Lack of autofluorescence in fundus albipunctatus associated with mutations in RDH5," Retina, vol.
Lindeman, "Spectraldomain optical coherence tomography and fundus autofluorescence characteristics in patients with fundus albipunctatus and retinitis punctata albescens," Ophthalmic Genetics, vol.