functional pleiotropy

func·tion·al plei·ot·ro·py

the pleiotropy due to the participation of the same allelic change in multiple otherwise distinct processes; for example, heparin is active in many body reactions including coagulation and the metabolism of fat.
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In fact, if, from one side, their functional pleiotropy guarantees multiple therapeutic and preventive effects, their low bioavailability and high metabolic transformation represent an unsolved issue on the way to demonstrate a clear structure-function relationship in regulating cellular physiology.
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